Evidence map›Paper›PMID 30649630›Full record

ArticleMikrochimica acta2019

Graphene oxide with in-situ grown Prussian Blue as an electrochemical probe for microRNA-122.

Feng Wang, Yaru Chu, Yijing Ai, Lin Chen, Feng Gao

Abstract read
PubMed Publisher
In one paragraph

Article in Mikrochimica acta, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
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  7. Graphene/MoSMaterials (Basel, Switzerland) · 2021
    Review
  8. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Feng WangDepartment of Clinical Laboratory, Affiliated Hospital of Nantong University, Nantong, Jiangsu, 226001, People's Republic of China.
Yaru ChuCollege of Chemistry and Environment, Fujian Province Key Laboratory of Morden Analytical Science and Separation Technology, Minnan Normal University, Zhangzhou, 363000, People's Republic of China.
Yijing AiCollege of Chemistry and Environment, Fujian Province Key Laboratory of Morden Analytical Science and Separation Technology, Minnan Normal University, Zhangzhou, 363000, People's Republic of China.
Lin ChenDepartment of Gastroenterology and Clinical Laboratory, Nantong Third Hospital Affiliated to Nantong University, Nantong, Jiangsu, 226006, People's Republic of China.
Feng GaoCollege of Chemistry and Environment, Fujian Province Key Laboratory of Morden Analytical Science and Separation Technology, Minnan Normal University, Zhangzhou, 363000, People's Republic of China. fgao1981@mnnu.edu.cn.

Funding

National Natural Science Foundation of China 21802064National Natural Science Foundation of China (CN) 81601842National Natural Science Foundation of China (CN) 81873978Six Talent Peaks Project in Jiangsu Province 2018-WSW-068the 64th grant of Chinese Post-doctoral Science Foundation 2018M642298
6 · The paper itself

Abstract

An electrochemical biosensor for microRNA was constructed on the basis of direct growth of electroactive Prussian Blue (PB) on graphene oxide (GO). A mercapto-modified probe DNA that is complementary to the hepatocellular carcinoma biomarker microRNA-122 was firstly anchored on a gold electrode (AuE). Then, GO (with its large surface and multiple active sites) was adsorbed on probe DNA through π-interaction. Subsequently, the PB nanoparticles were directly grown on GO via alternative dipping the electrode in solutions of FeCl

Indexed as

ElectrochemistryFerrocyanidesGraphiteHumansLimit of DetectionMicroRNAsOxidesferric ferrocyanideFerrocyanidesGraphiteMicroRNAsMIRN122 microRNA, humanOxidesAtomic force microscopyBase-pairing principleLiver injury biomarkerNanosize effectScanning electron microscopyUV-vis spectraπ-stacking

Identifiers

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.