Evidence map›Paper›PMID 30649617›Full record

ArticleJournal of neurology2019

Factors interfering with parenthood decision-making in an Italian sample of people with multiple sclerosis: an exploratory online survey.

L Lavorgna, S Esposito, R Lanzillo, M Sparaco, D Ippolito, E Cocco, G Fenu, G Borriello, S De Mercanti, J Frau and 8 more

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
  11. Sex effects across the lifespan in women with multiple sclerosis.Therapeutic advances in neurological disorders · 2020
    Review
  12. Family planning in Argentinian women with multiple sclerosis: An important yet seldom approached issue.Multiple sclerosis journal - experimental, translational and clinical
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 5 institutions in 1 country.

L LavorgnaFirst Division of Neurology, University of Campania Luigi Vanvitelli, Piazza Miraglia, 2, 80138, Naples, Italy. luigi.lavorgna@policliniconapoli.it.ORCID http://orcid.org/0000-0003-4625-4236
S EspositoFirst Division of Neurology, University of Campania Luigi Vanvitelli, Piazza Miraglia, 2, 80138, Naples, Italy.
R LanzilloDepartment of Neurosciences, Reproductive Sciences and Odontostomatology, University Federico II, Naples, Italy.
M SparacoFirst Division of Neurology, University of Campania Luigi Vanvitelli, Piazza Miraglia, 2, 80138, Naples, Italy.
D IppolitoFirst Division of Neurology, University of Campania Luigi Vanvitelli, Piazza Miraglia, 2, 80138, Naples, Italy.
E CoccoDepartment of Medical Sciences and Public Health, Multiple Sclerosis Centre, Binaghi Hospital, University of Cagliari, Cagliari, Italy.
G FenuDepartment of Medical Sciences and Public Health, Multiple Sclerosis Centre, Binaghi Hospital, University of Cagliari, Cagliari, Italy.
G BorrielloDepartment of Neurology and Psychiatry, S. Andrea MS Center, Sapienza University, Rome, Italy.
S De MercantiClinical and Biological Sciences Department, University of Torino, Turin, Italy.
J FrauDepartment of Medical Sciences and Public Health, Multiple Sclerosis Centre, Binaghi Hospital, University of Cagliari, Cagliari, Italy.
R CapuanoFirst Division of Neurology, University of Campania Luigi Vanvitelli, Piazza Miraglia, 2, 80138, Naples, Italy.
F TrojsiFirst Division of Neurology, University of Campania Luigi Vanvitelli, Piazza Miraglia, 2, 80138, Naples, Italy.
L RosaDepartment of Neurosciences, Reproductive Sciences and Odontostomatology, University Federico II, Naples, Italy.
M ClericoClinical and Biological Sciences Department, University of Torino, Turin, Italy.
A LaroniDepartment of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, IRCCS AOU San Martino-IST, University of Genoa, Genoa, Italy.
V Brescia MorraDepartment of Neurosciences, Reproductive Sciences and Odontostomatology, University Federico II, Naples, Italy.
G TedeschiFirst Division of Neurology, University of Campania Luigi Vanvitelli, Piazza Miraglia, 2, 80138, Naples, Italy.
S BonavitaFirst Division of Neurology, University of Campania Luigi Vanvitelli, Piazza Miraglia, 2, 80138, Naples, Italy.
University of Campania "Luigi Vanvitelli" · ITUniversity of Cagliari · ITUniversity of Turin · ITOspedale Policlinico San Martino · ITSapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLittle is known about the influence of multiple sclerosis (MS) diagnosis on parenthood attitude in people with MS (pwMS).

objectiveTo investigate the impact of diagnosis, clinical features and external disease-related influences on parenthood decision-making in Italian pwMS.

methodsA web-based survey was posted on SMsocialnetwork.com to investigate clinical status, parenthood desire, influences on family planning, pregnancy outcomes, abortions and adoptions of pwMS.

results33/395 respondents never wanted to become parent because of MS ("anti-parenthood after diagnosis"). 362 declared to be in favor of parenthood. 51% pwMS having a child by the survey time had already received the MS diagnosis at first childbirth. The frequency of a second child in pwMS after diagnosis was 38% compared to 67% in people without yet MS diagnosis. 16% of pwMS were discouraged to become parent after diagnosis, mainly by medical personnel. In 71% of respondents, diagnosis did not delay the decision to become parent and only 39% were counseled by treating physician to plan pregnancy. Patients' distribution according to the clinical phenotype (exclusively relapsing vs exclusively progressive) showed a higher proportion of progressive patients in the "anti-parenthood after diagnosis" subgroup.

conclusionMS diagnosis impacted dramatically on the life project of 7% of pwMS that decided not to have children because of the disease and in pro-parenthood pwMS impacted especially on having the second child. Only a minority was counseled to plan pregnancy. A worse disease course driving to a progressive phenotype at survey time might have negatively impacted on parenthood desire.

Indexed as

Online SystemsAdultDecision MakingFemaleHumansItalyMaleMiddle AgedMultiple SclerosisParentsStatistics, Nonparametrice-healthMultiple sclerosisOnline surveyParenthood

Identifiers

PMID30649617
OpenAlexW2909725910

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.