Evidence map›Paper›PMID 30649491›Full record

ReviewNeuro-oncology2019

Imaging and diagnostic advances for intracranial meningiomas.

Raymond Y Huang, Wenya Linda Bi, Brent Griffith, Timothy J Kaufmann, Christian la Fougère, Nils Ole Schmidt, Jöerg C Tonn, Michael A Vogelbaum, Patrick Y Wen, Kenneth Aldape and 4 more

Open access · bronzeAbstract readReview
In one paragraph

Review in Neuro-oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 91 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
91citing papers in PubMed, 3 pooled it
8.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

91 citing papers in PubMed, 3 syntheses or guidelines pooled it, 185 citations in OpenAlex.

  1. Pooled it
  2. Guideline
  3. Pooled it
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  6. Review
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  15. SUV-max ofJournal of neuro-oncology · 2025
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31 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 9 institutions in 3 countries.

Raymond Y HuangDepartment of Radiology, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Wenya Linda BiCenter for Skull Base and Pituitary Surgery, Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Brent GriffithDepartment of Radiology, Henry Ford Health System, Detroit, Michigan, USA.
Timothy J KaufmannDepartment of Radiology, Mayo Clinic and Foundation, Rochester, Minnesota, USA.
Christian la FougèreNuclear Medicine and Clinical Molecular Imaging, University Hospital Tubingen, Tubingen, Germany.
Nils Ole SchmidtDepartment of Neurosurgery, University Medical Center, Hamburg-Eppendorf, Germany.
Jöerg C TonnDepartment of Neurosurgery, Ludwig-Maximilians-University Munich, Munich, Germany.
Michael A VogelbaumRose Ella Burkhardt Brain Tumor and Neuro-Oncology Center, Department of Neurosurgery, Neurological Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Patrick Y WenCenter for Neuro-Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.
Kenneth AldapeDepartment of Laboratory Pathology, National Cancer Institute, National Institute of Health, Bethesda, Maryland, USA.
Farshad NassiriDivision of Neurosurgery, University Health Network, University of Toronto, Ontario, Canada.
Gelareh ZadehDivision of Neurosurgery, University Health Network, University of Toronto, Ontario, Canada.
Ian F DunnCenter for Skull Base and Pituitary Surgery, Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
International Consortium on Meningiomas
Brigham and Women's Hospital · USUniversity Health Network · CACleveland Clinic · USHenry Ford Health System · USLudwig-Maximilians-Universität München · DEUniversität Hamburg · DECenter for Neuro-Oncology · USMayo Clinic · USPrincess Margaret Cancer Centre · CA

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
Development and validation of a predictor of meningioma recurrenceZIABC011847 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI ALDAPE, KENNETH · 2018 to 2025
$5.9M
Targeting histone demethylase activity for the treatment of pediatric brainstem gliomaR01NS093079 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI HASHIZUME, RINTARO · 2015 to 2019
$1.5M
NCATS NIH HHS UL1 TR001422NINDS NIH HHS R01 NS093079
6 · The paper itself

Abstract

The archetypal imaging characteristics of meningiomas are among the most stereotypic of all central nervous system (CNS) tumors. In the era of plain film and ventriculography, imaging was only performed if a mass was suspected, and their results were more suggestive than definitive. Following more than a century of technological development, we can now rely on imaging to non-invasively diagnose meningioma with great confidence and precisely delineate the locations of these tumors relative to their surrounding structures to inform treatment planning. Asymptomatic meningiomas may be identified and their growth monitored over time; moreover, imaging routinely serves as an essential tool to survey tumor burden at various stages during the course of treatment, thereby providing guidance on their effectiveness or the need for further intervention. Modern radiological techniques are expanding the power of imaging from tumor detection and monitoring to include extraction of biologic information from advanced analysis of radiological parameters. These contemporary approaches have led to promising attempts to predict tumor grade and, in turn, contribute prognostic data. In this supplement article, we review important current and future aspects of imaging in the diagnosis and management of meningioma, including conventional and advanced imaging techniques using CT, MRI, and nuclear medicine.

Indexed as

HumansMeningeal NeoplasmsMeningiomaMultimodal ImagingNeuroimaging

Identifiers

PMID30649491
PMCPMC6347083
OpenAlexW2908578072

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.