ArticleGenome biology and evolution2019
The Chemosensory Receptor Repertoire of a True Shark Is Dominated by a Single Olfactory Receptor Family.
Article in Genome biology and evolution, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 47 citations in OpenAlex.
- Vertebrate-wide transcriptomic screening identifies immune cell-specific expression of the conserved OR-κ gene.Zoological letters · 2026Article
- Hagfish olfactory repertoire illuminates lineage-specific diversification of olfaction in basal vertebrates.iScience · 2025Article
- Divergent selection, recombination variability, and noncoding introgression drive speciation and adaptation in threadfin Eleutheronema.Communications biology · 2025Article
- Decoding deception: the binding affinity of cuttlefish ink on shark smell receptors.G3 (Bethesda, Md.) · 2025Article
- The Sensory Shark: High-quality Morphological, Genomic and Transcriptomic Data for the Small-spotted Catshark Scyliorhinus Canicula Reveal the Molecular Bases of Sensory Organ Evolution in Jawed Vertebrates.Molecular biology and evolution · 2024Article
- The Remarkable Diversity of Vertebrate Bitter Taste Receptors: Recent Advances in Genomic and Functional Studies.International journal of molecular sciences · 2024Review
- Diversity and evolution of the vertebrate chemoreceptor gene repertoire.Nature communications · 2024Article
- A vertebrate-wide catalogue of T1R receptors reveals diversity in taste perception.Nature ecology & evolution · 2024Article
- A singular shark bitter taste receptor provides insights into the evolution of bitter taste perception.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Chromosome-level genome assembly of the deep-sea snail Phymorhynchus buccinoides provides insights into the adaptation to the cold seep habitat.BMC genomics · 2023Article
- Ancient and Nonuniform Loss of Olfactory Receptor Expression Renders the Shark Nose a De Facto Vomeronasal Organ.Molecular biology and evolution · 2023Article
- Coevolution of the olfactory organ and its receptor repertoire in ray-finned fishes.BMC biology · 2022Article
- Remarkable diversity of vomeronasal type 2 receptor (OlfC) genes of basal ray-finned fish and its evolutionary trajectory in jawed vertebrates.Scientific reports · 2022Article
- Evolution of Brain-Expressed Biogenic Amine Receptors into Olfactory Trace Amine-Associated Receptors.Molecular biology and evolution · 2022Article
- Evolutionary Dynamics of the OR Gene Repertoire in Teleost Fishes: Evidence of an Association with Changes in Olfactory Epithelium Shape.Molecular biology and evolution · 2021Article
- Olfactory function in the trace amine-associated receptor family (TAARs) evolved twice independently.Scientific reports · 2021Article
- Coding of pheromones by vomeronasal receptors.Cell and tissue research · 2021Review
- Bitter taste receptors: Genes, evolution and health.Evolution, medicine, and public health · 2021Review
- The evolutionary origins of the vertebrate olfactory system.Open biology · 2020Review
- TAAR Agonists.Cellular and molecular neurobiology · 2020Review
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Throughout the animal kingdom chemical senses are one of the primary means by which organisms make sense of their environment. To achieve perception of complex chemosensory stimuli large repertoires of olfactory and gustatory receptors are employed in bony vertebrates, which are characterized by high evolutionary dynamics in receptor repertoire size and composition. However, little is known about their evolution in earlier diverging vertebrates such as cartilaginous fish, which include sharks, skates, rays, and chimeras. Recently, the olfactory repertoire of a chimera, elephant shark, was found to be curiously reduced in odorant receptor number. Elephant sharks rely heavily on electroreception to localize prey; thus, it is unclear how representative their chemosensory receptor repertoire sizes would be for cartilaginous fishes in general. Here, we have mined the genome of a true shark, Scyliorhinus canicula (catshark) for olfactory and gustatory receptors, and have performed a thorough phylogenetic study to shed light on the evolution of chemosensory receptors in cartilaginous fish. We report the presence of several gustatory receptors of the TAS1R family in catshark and elephant shark, whereas TAS2R receptors are absent. The catshark olfactory repertoire is dominated by V2R receptors, with 5-8 receptors in the other three families (OR, ORA, TAAR). Species-specific expansions are mostly limited to the V2R family. Overall, the catshark chemosensory receptor repertoires are generally similar in size to those of elephant shark, if somewhat larger, showing similar evolutionary tendencies across over 400 Myr of separate evolution between catshark and elephant shark.
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