Evidence map›Paper›PMID 30649009›Full record

ArticleJournal of occupational and environmental medicine2019

Shiftwork and Biomarkers of Subclinical Cardiovascular Disease: The BCOPS Study.

Meghan M Holst, Michael D Wirth, Anna Mnatsakanova, James B Burch, Luenda E Charles, Cathy Tinney-Zara, Desta Fekedulegn, Michael E Andrew, Tara A Hartley, John M Violanti

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In one paragraph

Article in Journal of occupational and environmental medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Systematic review of drugs that modify the circadian system's phase-shifting responses to light exposure.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2022
    Pooled it
  3. Review
  4. Review
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Meghan M HolstDepartment of Epidemiology and Biostatistics, Arnold School of Public Health (Mr Holst, Dr Wirth, Dr Burch); Cancer Prevention and Control Program (Dr Wirth, Dr Burch); College of Nursing (Dr Wirth), University of South Carolina; Biostatistics and Epidemiology Branch, Health Effects Laboratory Division, National Institute for Occupational Safety and Health, Centers for Disease Control and Prevention, Morgantown, West Virginia (Ms Mnatsakanova, Dr Charles, Ms Tinney-Zara, Dr Fekedulegn, Dr Andrew, Dr Hartley); WJB Dorn VA Medical Center (Dr Burch), Columbia, South Carolina; Department of Epidemiology and Environmental Health, School of Public Health and Health Professions, University of Buffalo, The State University of New York, Buffalo, New York (Dr Violanti).
Michael D Wirth
Anna Mnatsakanova
James B Burch
Luenda E Charles
Cathy Tinney-Zara
Desta Fekedulegn
Michael E Andrew
Tara A Hartley
John M Violanti

Funding

Stress and Subclinical Cardio-Metabolic Disease in Police: A Longitudinal StudyR01OH009640 · OH · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI VIOLANTI, JOHN M · 2010 to 2014
$2.7M
Stressors and Cardio-Metabolic Disease in Police: A 12-year Longitudinal StudyR01OH010807 · OH · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI VIOLANTI, JOHN M · 2015 to 2018
$2.6M
NIOSH CDC HHS R01 OH009640NIOSH CDC HHS R01 OH010807
6 · The paper itself

Abstract

objectiveTo assess the association of shiftwork with biomarkers of subclinical cardiovascular disease and examine the moderating role of body mass index (BMI) in a police cohort.

methodsA cross-sectional analysis was conducted among officers who were categorized as working the day, evening, or night shift. Comparisons with inflammatory biomarkers were performed among shifts using analysis of variance/covariance and further stratified by BMI to assess potential effect modification.

resultsAssociations were observed between day and night shiftworkers for leukocytes, tumor necrosis factor alpha, and homocysteine. After BMI stratification, higher c-reactive protein (CRP) levels were observed among evening shiftworkers with a BMI more than or equal to 30 kg/m versus the day shift.

conclusionsFuture studies examining prospective changes in these markers will allow for more comprehensive evaluation of their association with shiftwork.

Indexed as

AdultBiomarkersBody Mass IndexCardiovascular DiseasesCross-Sectional StudiesHumansMaleMiddle AgedWork Schedule ToleranceBiomarkers

Identifiers

PMID30649009
PMCPMC6610651

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.