Evidence map›Paper›PMID 30648971›Full record

ArticleeLife2019

The presence and absence of periplasmic rings in bacterial flagellar motors correlates with stator type.

Mohammed Kaplan, Debnath Ghosal, Poorna Subramanian, Catherine M Oikonomou, Andreas Kjaer, Sahand Pirbadian, Davi R Ortega, Ariane Briegel, Mohamed Y El-Naggar, Grant J Jensen

Abstract read
In one paragraph

Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Journal of bacteriology · 2026
    Review
  2. The ancient E-ring in bacterial flagellar motors.FEMS microbiology reviews · 2026
    Review
  3. Article
  4. Tetrameric PilZ protein stabilizes stator ring in complex flagellar motor and is required for motility inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  5. HowmBio · 2024
    Article
  6. Article
  7. Structure and Assembly of theInternational journal of molecular sciences · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Bacterial flagellar motor PL-ring disassembly subcomplexes are widespread and ancient.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mohammed KaplanDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.ORCID 0000-0002-0759-0459
Debnath GhosalDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.
Poorna SubramanianDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.
Catherine M OikonomouDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.
Andreas KjaerDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.ORCID 0000-0002-0096-5764
Sahand PirbadianDepartment of Physics and Astronomy, Biological Sciences, and Chemistry, University of Southern California, Los Angeles, United States.
Davi R OrtegaDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.
Ariane BriegelDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.ORCID 0000-0003-3733-3725
Mohamed Y El-NaggarDepartment of Physics and Astronomy, Biological Sciences, and Chemistry, University of Southern California, Los Angeles, United States.
Grant J JensenDivision of Biology and Biological Engineering, California Institute of Technology, Pasadena, United States.ORCID 0000-0003-1556-4864

Funding

Structure and Function of Pathogenesis-Associated Bacterial Structures by Electron CryotomographyR01AI127401 · NIAID · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI GRANT J JENSEN · 2016 to 2026
$3.9M
Air Force Office of Scientific Research FA955014-1-0294Nederlandse Organisatie voor Wetenschappelijk Onderzoek Rubicon fellowshipNIAID NIH HHS R01 AI127401NIH HHS R01 AI127401
6 · The paper itself

Abstract

The bacterial flagellar motor, a cell-envelope-embedded macromolecular machine that functions as a cellular propeller, exhibits significant structural variability between species. Different torque-generating stator modules allow motors to operate in different pH, salt or viscosity levels. How such diversity evolved is unknown. Here, we use electron cryo-tomography to determine the in situ macromolecular structures of three Gammaproteobacteria motors:

Indexed as

FlagellaGammaproteobacteriaMolecular Motor ProteinsPeriplasmPhylogenySodiumMolecular Motor ProteinsSodiumbacterial flagellar motorelectron cryo-tomographyevolutionevolutionary biologyinfectious diseaseLegionella pneumophilamicrobiologyPseudomonas aeruginosaShewanella oneidensis MR-1

Identifiers

PMID30648971
PMCPMC6375700

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.