ArticleJournal of neuroimaging : official journal of the American Society of Neuroimaging2019
Functional MRI Task Comparison for Language Mapping in Neurosurgical Patients.
Article in Journal of neuroimaging : official journal of the American Society of Neuroimaging, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07650994 (Naturalistic Neuroimaging for Neurosurgical Brain Mapping), which is not on this map. Cited by 28 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Naturalistic Neuroimaging for Neurosurgical Brain Mapping
Who cites it
28 citing papers in PubMed.
- Language mapped to a high-resolution brain atlas for surgical evaluation of epilepsy patients.Epilepsia · 2026Article
- Resting-State vs. Task-Based Functional Magnetic Resonance Imaging in Neurosurgical Planning: A Narrative Review of Clinical Applications.Biomedicines · 2026Review
- Persian Paradigm for Language Cortical Mapping: Development, Feasibility, and Evaluation.Brain and behavior · 2026Article
- A Rapid fMRI Paradigm for Localisation of the Language Network.The European journal of neuroscience · 2026Article
- Advances in Preoperative and Intraoperative Technologies for Safe Resection of Gliomas in Cognitive Regions.Cancers · 2025Review
- Consensus recommendations for clinical functional MRI applied to language mapping.Aperture neuro · 2025Article
- Probabilistic Presurgical Language fMRI Atlas of Patients with Brain Tumors.AJNR. American journal of neuroradiology · 2024Article
- Fibration symmetry-breaking supports functional transitions in a brain network engaged in language.ArXiv · 2024Article
- Utilizing connectome fingerprinting functional MRI models for motor activity prediction in presurgical planning: A feasibility study.Human brain mapping · 2024Article
- Fibration symmetry-breaking supports functional transitions in a brain network engaged in language.Research square · 2024Article
- A comparison of fMRI presurgical mapping techniques with intraoperative brain mapping-based validation.Imaging neuroscience (Cambridge, Mass.) · 2024Article
- Effect of tumor genetics, pathology, and location on fMRI of language reorganization in brain tumor patients.European radiology · 2023Article
- Beyond Broca's and Wernicke's: Functional Mapping of Ancillary Language Centers Prior to Brain Tumor Surgery.Tomography (Ann Arbor, Mich.) · 2023Review
- Repetitive transcranial magnetic stimulation modulates action naming over the left but not right inferior frontal gyrus.Brain structure & function · 2022Article
- Understanding Language Reorganization With Neuroimaging: How Language Adapts to Different Focal Lesions and Insights Into Clinical Applications.Frontiers in human neuroscience · 2022Review
- A New Functional Magnetic Resonance Imaging Localizer for Preoperative Language Mapping Using a Sentence Completion Task: Validity, Choice of Baseline Condition, and Test-Retest Reliability.Frontiers in human neuroscience · 2022Article
- Clinical Pearls and Methods for Intraoperative Awake Language Mapping.Neurosurgery · 2021Review
- Feasibility, Contrast Sensitivity and Network Specificity of Language fMRI in Presurgical Evaluation for Epilepsy and Brain Tumor Surgery.Brain topography · 2021Article
- The impact of high functional connectivity network hub resection on language task performance in adult low- and high-grade glioma.Journal of neurosurgery · 2021Article
- A Data-Based Approach for Selecting Pre- and Intra-Operative Language Mapping Tasks.Frontiers in neuroscience · 2021Article
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
background and purposeLanguage task-based functional MRI (fMRI) is increasingly used for presurgical planning in patients with brain lesions. Different paradigms elicit activations of different components of the language network. The aim of this study is to optimize fMRI clinical usage by comparing the effectiveness of three language tasks for language lateralization and localization in a large group of patients with brain lesions.
methodsWe analyzed fMRI data from a sequential retrospective cohort of 51 patients with brain lesions who underwent presurgical fMRI language mapping. We compared the effectiveness of three language tasks (Antonym Generation, Sentence Completion (SC), and Auditory Naming) for lateralizing language function and for activating cortex within patient-specific regions-of-interest representing eloquent language areas, and assessed the degree of spatial overlap of the areas of activation elicited by each task.
resultsThe tasks were similarly effective for lateralizing language within the anterior language areas. The SC task produced higher laterality indices within the posterior language areas and had a significantly higher agreement with the clinical report. Dice coefficients between the task pairs were in the range of .351-.458, confirming substantial variation in the components of the language network activated by each task.
conclusionsSC task consistently produced large activations within the dominant hemisphere and was more effective for lateralizing language within the posterior language areas. The low degree of spatial overlap among the tasks strongly supports the practice of using a battery of tasks to help the surgeon to avoid eloquent language areas.
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