Evidence map›Paper›PMID 30648756›Full record

ArticleEnvironmental toxicology and chemistry2019

Aryl hydrocarbon receptor-mediated activity of gas-phase ambient air derived from passive sampling and an in vitro bioassay.

Carrie A McDonough, Diana G Franks, Mark E Hahn, Rainer Lohmann

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Environmental toxicology and chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Carrie A McDonoughUniversity of Rhode Island Graduate School of Oceanography, Narragansett, Rhode Island, USA.
Diana G FranksBiology Department, Woods Hole Oceanographic Institution, Woods Hole, Massachusetts, USA.
Mark E HahnBiology Department, Woods Hole Oceanographic Institution, Woods Hole, Massachusetts, USA.
Rainer LohmannUniversity of Rhode Island Graduate School of Oceanography, Narragansett, Rhode Island, USA.

Funding

Training CoreP42ES007381 · NIEHS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI HAHN, MARK E · 1995 to 2019
$46.1M
NIEHS NIH HHS P42 ES007381Superfund Basic Research Program at Boston UniversityUS Environmental Protection Agency Great Lakes Restoration Initiative 00E00597-0US Environmental Protection Agency Great Lakes Restoration Initiative P42ES007381
6 · The paper itself

Abstract

The gaseous fraction of hydrophobic organic contaminants (HOCs) in ambient air appears to be responsible for a significant portion of aryl hydrocarbon receptor (AhR)-mediated activity, but the majority of compounds contributing to this activity remain unidentified. The present study investigated the use of polyethylene passive samplers to isolate gaseous HOCs from ambient air for use in in vitro bioassays and to improve our understanding of the toxicological relevance of the gaseous fraction of ambient air in urban and residential environments. Concentrations of polycyclic aromatic hydrocarbons (PAHs) and organic flame retardants were measured in polyethylene passive sampler extracts. Extracts were also analyzed using an in vitro bioassay to measure AhR-mediated activity. Bioassay-derived benzo[a]pyrene (BaP) equivalents (BaP-Eq

Indexed as

AirAir PollutantsAnimalsBiological AssayCell Line, TumorEnvironmental MonitoringGenes, ReporterGreen Fluorescent ProteinsMicePolycyclic Aromatic HydrocarbonsReceptors, Aryl HydrocarbonTransfectionAir PollutantsGreen Fluorescent ProteinsPolycyclic Aromatic HydrocarbonsReceptors, Aryl HydrocarbonAryl hydrocarbon receptorFlame retardantsMixture toxicologyOrganophosphate estersPassive samplerPolycyclic aromatic hydrocarbons

Identifiers

PMID30648756
PMCPMC6467651

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.