ArticleeLife2019
An afferent white matter pathway from the pulvinar to the amygdala facilitates fear recognition.
Article in eLife, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers, 1 of them a synthesis that pooled it.
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Who cites it
63 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Networks underpinning emotion: A systematic review and synthesis of functional and effective connectivity.NeuroImage · 2021Pooled it
- Distinct Visual Pathways of Threat Retrieval in Fear-Conditioned Faces.Psychophysiology · 2026Article
- Weakening of Subcortical and Strengthening of Cortical Visual Pathways Across Early Adolescence.Human brain mapping · 2026Article
- Fusiform face area development correlates with development in higher-order social brain regions.Developmental cognitive neuroscience · 2026Article
- Seeing Through Feeling: Dynamic Interplay Between Emotion and Visual Perception.Brain sciences · 2026Review
- A conserved pulvinar projection to the amygdala revealed in macaque monkeys (Macaca mulatta).Brain structure & function · 2026Article
- A Direct Auditory Subcortical Route to the Amygdala Associated with Fear in Humans.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026Article
- Explicit and Implicit Emotion Processing: The Role of Spatial Frequencies in a Case Study of Right Capsulo-Thalamic Damage.Journal of Intelligence · 2026Article
- Human superior colliculus pathways represent the form and motion of looming objects.Cell reports · 2026Article
- Widespread Corticothalamic Connectivity Identifies the Inferior Pulvinar as a Central Node in Visual Network Architecture.bioRxiv : the preprint server for biology · 2026Article
- Pulvinar-posterior superior temporal sulcus connectivity contributes to non-conscious emotion processing in affective blindsight.Cerebral cortex (New York, N.Y. : 1991) · 2026Article
- Alcohol-seeking associations with resting state functional connectivity of the amygdala.Drug and alcohol dependence · 2026Article
- Double dissociation of dynamic and static face perception provides causal evidence for a third visual pathway.Nature communications · 2025Article
- Neural Representation of Associative Threat Learning in Pulvinar Divisions, Lateral Geniculate Nucleus, and Mediodorsal Thalamus in Humans.bioRxiv : the preprint server for biology · 2025Article
- Track-Weighted Dynamic Functional Connectivity Profiles and Topographic Organization of the Human Pulvinar.Human brain mapping · 2024Article
- Anatomo-functional basis of emotional and motor resonance elicited by facial expressions.Brain : a journal of neurology · 2024Article
- Visual looming is a primitive for human emotion.iScience · 2024Article
- Implicit Selective Attention: The Role of the Mesencephalic-basal Ganglia System.Current neuropharmacology · 2024Review
- Behavioral and neuroanatomical correlates of facial emotion processing in post-stroke depression.NeuroImage. Clinical · 2024Article
- Evidence for adaptive myelination of subcortical shortcuts for visual motion perception in healthy adults.Human brain mapping · 2023Article
3 more citing papers are in PubMed but not listed here.
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3 authors.
Funding
Abstract
Our ability to rapidly detect threats is thought to be subserved by a subcortical pathway that quickly conveys visual information to the amygdala. This neural shortcut has been demonstrated in animals but has rarely been shown in the human brain. Importantly, it remains unclear whether such a pathway might influence neural activity and behavior. We conducted a multimodal neuroimaging study of 622 participants from the Human Connectome Project. We applied probabilistic tractography to diffusion-weighted images, reconstructing a subcortical pathway to the amygdala from the superior colliculus via the pulvinar. We then computationally modeled the flow of haemodynamic activity during a face-viewing task and found evidence for a functionally afferent pulvinar-amygdala pathway. Critically, individuals with greater fibre density in this pathway also had stronger dynamic coupling and enhanced fearful face recognition. Our findings provide converging evidence for the recruitment of an afferent subcortical pulvinar connection to the amygdala that facilitates fear recognition. Editorial note: This article has been through an editorial process in which the authors decide how to respond to the issues raised during peer review. The Reviewing Editor's assessment is that minor issues remain unresolved (see decision letter).
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.