Evidence map›Paper›PMID 30648404›Full record

ArticleAntioxidants & redox signaling2021

Selenoprotein M Promotes Hypothalamic Leptin Signaling and Thioredoxin Antioxidant Activity.

Ting Gong, Ann C Hashimoto, Alexandru R Sasuclark, Vedbar S Khadka, Alexandra Gurary, Matthew W Pitts

Open access · greenAbstract read
In one paragraph

Article in Antioxidants & redox signaling, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 56 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Single-nuclei transcriptome analysis of IgMFrontiers in immunology · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. Selenoproteins in Health.Molecules (Basel, Switzerland) · 2023
    Review
  14. "Alphabet" Selenoproteins: Their Characteristics and Physiological Roles.International journal of molecular sciences · 2023
    Review
  15. Deciphering the Role of Selenoprotein M.Antioxidants (Basel, Switzerland) · 2023
    Review
  16. Article
  17. "Alphabet" Selenoproteins: Implications in Pathology.International journal of molecular sciences · 2023
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ting GongDepartment of Molecular Biosciences and Bioengineering, University of Hawaii, Honolulu, Hawaii, USA.
Ann C HashimotoDepartment of Cell and Molecular Biology, Medical Microbiolgy, and Pharmacology, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, USA.
Alexandru R SasuclarkDepartment of Cell and Molecular Biology, Medical Microbiolgy, and Pharmacology, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, USA.
Vedbar S KhadkaBioinformatics Core in the Department of Complementary and Integrative Medicine, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, USA.
Alexandra GuraryDepartment of Tropical Medicine, Medical Microbiolgy, and Pharmacology, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, USA.
Matthew W PittsDepartment of Cell and Molecular Biology, Medical Microbiolgy, and Pharmacology, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, USA.
University of Hawaii System · US

Funding

UH Hilo COP A&RP20GM103466 · NIGMS · UNIVERSITY OF HAWAII AT MANOA · PI Peter R Hoffmann · 2012 to 2026
$60.3M
The Role of gp120 on Cardiovascular Disease in People Living with HIVU54MD007601 · NIMHD · UNIVERSITY OF HAWAII AT MANOA · PI Jerris Robert Hedges · 2017 to 2026
$59.5M
TRPA1 Physiology in Diabetes, Metabolic Syndrome, and MetabolismP20GM113134 · NIGMS · UNIVERSITY OF HAWAII AT MANOA · PI Kathryn Jaques Schunke · 2017 to 2026
$21.5M
RESEARCH DESIGN AND BIOSTATISTICS COREU54MD007584 · NIMHD · UNIVERSITY OF HAWAII AT MANOA · PI MOKUAU, NOREEN, SHIRAMIZU, BRUCE T · 2012 to 2018
$21.1M
RESEARCH DESIGN, BIOSTATISTICS AND RESEARCH ETHICS COREG12MD007601 · NIMHD · UNIVERSITY OF HAWAII AT MANOA · PI BERRY, MARLA J · 2012 to 2016
$13.0M
Small Grants ProgramP30GM114737 · NIGMS · UNIVERSITY OF HAWAII AT MANOA · PI NERURKAR, VIVEK RAMCHANDRA · 2015 to 2022
$8.1M
NIGMS NIH HHS P20 GM103466NIGMS NIH HHS P20 GM113134NIGMS NIH HHS P30 GM114737NIMHD NIH HHS G12 MD007601NIMHD NIH HHS U54 MD007584NIMHD NIH HHS U54 MD007601
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAntioxidantsHypothalamusLeptinMiceMice, Inbred C57BLMice, KnockoutSelenoproteinsSignal TransductionThioredoxinsAntioxidantsLeptinSelenoproteinsSepm protein, mouseThioredoxinsTxn1 protein, mouseendoplasmic reticulumhypothalamusleptinselenoproteinthioredoxin

Identifiers

PMID30648404
PMCPMC8617589
OpenAlexW2909168900

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.