Evidence map›Paper›PMID 30648344›Full record

ArticleInternational journal for numerical methods in biomedical engineering2019

A semi-active human digital twin model for detecting severity of carotid stenoses from head vibration-A coupled computational mechanics and computer vision method.

Neeraj Kavan Chakshu, Jason Carson, Igor Sazonov, Perumal Nithiarasu

Abstract read
In one paragraph

Article in International journal for numerical methods in biomedical engineering, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  14. An AI based digital-twin for prioritising pneumonia patient treatment.Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine · 2022
    Article
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  16. Review
  17. A Scoping Review of Digital Twins in the Context of the Covid-19 Pandemic.Biomedical engineering and computational biology · 2022
    Article
  18. Digital Twins for Multiple Sclerosis.Frontiers in immunology · 2021
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Neeraj Kavan ChakshuBiomedical Engineering Group, Zienkiewicz Centre for Computational Engineering, College of Engineering, Swansea University, Swansea, SA2 8PP, UK.ORCID 0000-0002-6430-7939
Jason CarsonBiomedical Engineering Group, Zienkiewicz Centre for Computational Engineering, College of Engineering, Swansea University, Swansea, SA2 8PP, UK.ORCID 0000-0001-6634-9123
Igor SazonovBiomedical Engineering Group, Zienkiewicz Centre for Computational Engineering, College of Engineering, Swansea University, Swansea, SA2 8PP, UK.
Perumal NithiarasuBiomedical Engineering Group, Zienkiewicz Centre for Computational Engineering, College of Engineering, Swansea University, Swansea, SA2 8PP, UK.

Funding

Medical Research Council MR/S004076/1
6 · The paper itself

Abstract

In this work, we propose a methodology to detect the severity of carotid stenosis from a video of a human face with the help of a coupled blood flow and head vibration model. This semi-active digital twin model is an attempt to link noninvasive video of a patient face to the percentage of carotid occlusion. The pulsatile nature of blood flow through the carotid arteries induces a subtle head vibration. This vibration is a potential indicator of carotid stenosis severity, and it is exploited in the present study. A head vibration model has been proposed in the present work that is linked to the forces generated by blood flow with or without occlusion. The model is used to generate a large number of virtual head vibration data for different degrees of occlusion. In order to determine the in vivo head vibration, a computer vision algorithm is adopted to use human face videos. The in vivo vibrations are compared against the virtual vibration data generated from the coupled computational blood flow/vibration model. A comparison of the in vivo vibration is made against the virtual data to find the best fit between in vivo and virtual data. The preliminary results on healthy subjects and a patient clearly indicate that the model is accurate and it possesses the potential for detecting approximate severity of carotid artery stenoses.

Indexed as

HeadAdultAged, 80 and overAlgorithmsCarotid StenosisDiagnosis, Computer-AssistedFaceHealthy VolunteersHemodynamicsHumansMiddle AgedModels, BiologicalModels, CardiovascularPrincipal Component AnalysisRegional Blood FlowSmartphonebiomechanical vibrationsblood flowcarotid stenosescomputer visiondigital twinface videosystemic circulation

Identifiers

PMID30648344
PMCPMC6593817

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.