ReviewF1000Research2018
Life on the fringe: microbial adaptation to growth on carbon monoxide.
Review in F1000Research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 59 citations in OpenAlex.
- Carbon monoxide oxidizers in soils of different ages from Piton de la Fournaise volcano.FEMS microbiology ecology · 2026Article
- Carboxydotrophic Acetogenesis in Alkaline Conditions Results in Transient Formate Production by the Halo-Alkaliphilic Acetogen Haloacetibacter carboxydivorans Gen. Nov. sp. Nov.Environmental microbiology reports · 2026Article
- Carbon monoxide-driven proton respiration enables facultative anaerobes to survive electron acceptor limitation.The ISME journal · 2026Article
- The diversity of exoplanetary environments and the search for signs of life beyond Earth.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025Review
- Guiding Microbial Crossroads: Syngas-Driven Valorisation of Anaerobic-Digestion Intermediates into Bio-Hydrogen and Volatile Fatty Acids.Bioengineering (Basel, Switzerland) · 2025Review
- Effects of Nitrate on Hydrogenogenic Carbon Monoxide Oxidation in Parageobacillus thermoglucosidasius.Environmental microbiology reports · 2025Article
- Characterization of a MHYT domain-coupled transcriptional regulator that responds to carbon monoxide.Nucleic acids research · 2024Article
- CO-driven electron and carbon flux fuels synergistic microbial reductive dechlorination.Microbiome · 2024Article
- Exploring Rhodospirillum rubrum response to high doses of carbon monoxide under light and dark conditions.Applied microbiology and biotechnology · 2024Article
- Novel thermophilic generaFrontiers in microbiology · 2024Article
- Current status of carbon monoxide dehydrogenases (CODH) and their potential for electrochemical applications.Bioresources and bioprocessing · 2023Review
- Isolation, Genomic Sequence and Physiological Characterization ofApplied and environmental microbiology · 2023Article
- Carbon Monoxide Production during Bio-Waste Composting under Different Temperature and Aeration Regimes.Materials (Basel, Switzerland) · 2023Article
- Natural carbon fixation and advances in synthetic engineering for redesigning and creating new fixation pathways.Journal of advanced research · 2023Review
- Improving carbon monoxide tolerance ofFrontiers in bioengineering and biotechnology · 2023Article
- Genome-resolved metagenomic analysis of Great Amazon Reef System sponge-associated Latescibacterota bacteria and their potential contributions to the host sponge and reef.Frontiers in microbiomes · 2023Article
- Anaerobic carboxydotrophy in sulfur-respiring haloarchaea from hypersaline lakes.The ISME journal · 2022Article
- Biome-specific distribution of Ni-containing carbon monoxide dehydrogenases.Extremophiles : life under extreme conditions · 2022Article
- Early processes in heme-based CO-sensing proteins.Frontiers in molecular biosciences · 2022Review
- Integrating greenhouse gas capture and C1 biotechnology: a key challenge for circular economy.Microbial biotechnology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microbial adaptation to extreme conditions takes many forms, including specialized metabolism which may be crucial to survival in adverse conditions. Here, we analyze the diversity and environmental importance of systems allowing microbial carbon monoxide (CO) metabolism. CO is a toxic gas that can poison most organisms because of its tight binding to metalloproteins. Microbial CO uptake was first noted by Kluyver and Schnellen in 1947, and since then many microbes using CO via oxidation have emerged. Many strains use molecular oxygen as the electron acceptor for aerobic oxidation of CO using Mo-containing CO oxidoreductase enzymes named CO dehydrogenase. Anaerobic carboxydotrophs oxidize CO using CooS enzymes that contain Ni/Fe catalytic centers and are unrelated to CO dehydrogenase. Though rare on Earth in free form, CO is an important intermediate compound in anaerobic carbon cycling, as it can be coupled to acetogenesis, methanogenesis, hydrogenogenesis, and metal reduction. Many microbial species-both bacteria and archaea-have been shown to use CO to conserve energy or fix cell carbon or both. Microbial CO formation is also very common. Carboxydotrophs thus glean energy and fix carbon from a "metabolic leftover" that is not consumed by, and is toxic to, most microorganisms. Surprisingly, many species are able to thrive under culture headspaces sometimes exceeding 1 atmosphere of CO. It appears that carboxydotrophs are adapted to provide a metabolic "currency exchange" system in microbial communities in which CO arising either abiotically or biogenically is converted to CO
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.