Evidence map›Paper›PMID 30647799›Full record

SynthesisDisease markers2018

Lack of Association between Interleukin-1

Seoung-Jin Hong, Sang Wook Kang, Su Kang Kim, Young Sik Kim, Ju Yeon Ban

Open access · hybridAbstract readMeta-Analysis
In one paragraph

Synthesis in Disease markers, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Association of Interleukin 1 Receptor Antagonist (International journal of molecular sciences · 2026
    Article
  2. Observational
  3. Observational
  4. Article
  5. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Seoung-Jin HongDepartment of Prosthodontics, Kyung Hee University Dental Hospital, Seoul, Republic of Korea.
Sang Wook KangDepartment of Dental Pharmacology, College of Dentistry, Dankook University, Cheonan, Republic of Korea.ORCID 0000-0001-7462-1510
Su Kang KimDepartment of Biomedical Laboratory Science, Catholic Kwandong University, Gangneung, Republic of Korea.ORCID 0000-0001-6178-8514
Young Sik KimManagement Research Institute, Kyung Hee University, Seoul, Republic of Korea.
Ju Yeon BanDepartment of Dental Pharmacology, College of Dentistry, Dankook University, Cheonan, Republic of Korea.ORCID 0000-0003-1992-5188
Dankook University · KRCatholic Kwandong University · KRKyung Hee University · KRKyung Hee University Dental Hospital · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInterleukin-1

objectiveThe aim of this study was to determine whether the IL-1 MATERIAL AND

methodsFor the case-control study, 51 patients with chronic periodontitis and 33 healthy control patients were recruited in the study. Genotyping was conducted by direct sequencing. SNPStats and SPSS 18.0 were used for the analysis of genetic data and to evaluate odds ratios, 95% confidence intervals, and

resultsIn our case-control study, no significant relationship was revealed between IL-1

conclusionEvidences from a case-control study and the meta-analysis suggest that IL-1

Indexed as

Polymorphism, Single NucleotideAsian PeopleCase-Control StudiesChronic PeriodontitisGenetic Association StudiesGenetic Predisposition to DiseaseHumansInterleukin-1betaLogistic ModelsOdds RatioRepublic of KoreaSequence Analysis, DNAIL1B protein, humanInterleukin-1beta

Identifiers

PMID30647799
PMCPMC6311801
OpenAlexW2905396156

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.