Evidence map›Paper›PMID 30647774›Full record

ArticlePatient safety in surgery2019

Low-grade infections as a possible cause of arthrofibrosis after total knee arthroplasty.

C Brückner, E Straube, I Petersen, S Sachse, P Keller, F Layher, G Matziolis, U Spiegl, D Zajonz, M Edel and 1 more

Open access · goldAbstract read
In one paragraph

Article in Patient safety in surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

C BrücknerOrthopaedic Professorship of the University Hospital Jena, Orthopaedic Department of the Waldkliniken Eisenberg, Eisenberg, Germany.
E Straube2Institute of Medical Microbiology, Friedrich-Schiller-University Jena, Jena, Germany.
I Petersen3Institute of Pathology, Friedrich-Schiller-University Jena, Jena, Germany.
S Sachse2Institute of Medical Microbiology, Friedrich-Schiller-University Jena, Jena, Germany.
P Keller2Institute of Medical Microbiology, Friedrich-Schiller-University Jena, Jena, Germany.
F LayherOrthopaedic Professorship of the University Hospital Jena, Orthopaedic Department of the Waldkliniken Eisenberg, Eisenberg, Germany.
G MatziolisOrthopaedic Professorship of the University Hospital Jena, Orthopaedic Department of the Waldkliniken Eisenberg, Eisenberg, Germany.
U Spiegl6Department of Orthopaedics, Traumatology and Plastic Surgery, University Hospital Leipzig, Leipzig, Germany.
D Zajonz6Department of Orthopaedics, Traumatology and Plastic Surgery, University Hospital Leipzig, Leipzig, Germany.
M EdelZESBO - Center for research on musculoskeletal systems, Leipzig, Germany.
A RothOrthopaedic Professorship of the University Hospital Jena, Orthopaedic Department of the Waldkliniken Eisenberg, Eisenberg, Germany.
Friedrich Schiller University Jena · DEUniversity Hospital Leipzig · DEWaldkrankenhaus Rudolf Elle · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeArthrofibrosis after total knee arthroplasty represents a considerable burden for the patient and a therapeutic challenge for the practitioner. One possible cause discussed in the literature is a low-grade infection. This hypothesis should be examined within the scope of this retrospective study. PATIENTS AND

methodsNineteen patients with clinical symptoms of arthrofibrosis after primary total knee arthroplasty were examined between January, 1999 and January, 2012. Incorrect positioning was radiologically ruled out. All patients were examined clinically (score of Freeman as well as Blauth and Jäger), radiologically (component and leg alignment, patella height according to Insall and Salvati), microbiologically (culture-based procedures), molecular biologically (PCR) and histologically in the course of an open revision of the prosthesis.

resultsAccording to the score of Freeman et al. (1977), a highly significant improvement in pain (

conclusionThe hypothesis of low-grade-infection-induced arthrofibrosis after total knee arthroplasty could not be confirmed in this study. However, based on this small study population the conclusion needs to be confirmed by new and larger studies, ideally prospectively designed including a control group.

Indexed as

ArthrofibrosisPCRTotal knee arthroplasty

Identifiers

PMID30647774
PMCPMC6327456
OpenAlexW2943593275

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.