Evidence map›Paper›PMID 30647762›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2018

Lakkyong Hwang, Il-Gyu Ko, Jun-Jang Jin, Sang-Hoon Kim, Chang-Ju Kim, Jung Won Jeon, Jin Hee Han

Abstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Effectiveness ofToxins · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Anti-inflammatory activities of arthropod peptides: a systematic review.The journal of venomous animals and toxins including tropical diseases · 2021
    Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lakkyong HwangDepartment of Physiology, College of Medicine, Kyung Hee University, Seoul 02447, Republic of Korea.
Il-Gyu KoDepartment of Physiology, College of Medicine, Kyung Hee University, Seoul 02447, Republic of Korea.
Jun-Jang JinDepartment of Physiology, College of Medicine, Kyung Hee University, Seoul 02447, Republic of Korea.
Sang-Hoon KimDepartment of Physiology, College of Medicine, Kyung Hee University, Seoul 02447, Republic of Korea.
Chang-Ju KimDepartment of Physiology, College of Medicine, Kyung Hee University, Seoul 02447, Republic of Korea.
Jung Won JeonDepartment of Internal Medicine, Kyung Hee University Hospital at Gangdong, College of Medicine, Kyung Hee University, Seoul 05278, Republic of Korea.
Jin Hee HanDepartment of Anesthesiology and Pain Medicine, College of Medicine, Kyung Hee University, Seoul 02447, Republic of Korea.ORCID 0000-0003-0399-1148

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSciatic nerve injury develops from a variety of pathological causes, including traumatic injury and neuroinflammatory disorders, which are accompanied by pathological changes that have a critical impact on neuropathic pain and locomotor activity. Extracts of

methodsTo estimate the anti-inflammatory effects of SSM, inflammatory conditions were induced using lipopolysaccharide (LPS) in RAW 264.7 cells, and inflammatory-related factors were evaluated by enzyme-linked immunosorbent assay (ELISA) and western blotting analyses. Sciatic nerve crush injury (SNCI) was induced in rats using a surgical clip instrument. The effects of SSM in the SNCI model were evaluated in behavioral tests by calculating the sciatic functional index (SFI) and measuring thermal hyperalgesia sensitivity and by monitoring inflammatory factors expression in western blotting analyses.

resultsWe observed the anti-inflammatory effects of SSM treatment both in vitro and in vivo. The PGE

conclusionsOur results suggest that SSM suppresses the production of inflammatory factors via the NF-

Identifiers

PMID30647762
PMCPMC6311788

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.