Evidence map›Paper›PMID 30647705›Full record

ArticleJournal, genetic engineering & biotechnology2018

Effect of vitamin A deficiency on thymosin-β4 and CD4 concentrations.

Salwa Refat El-Zayat, Hiba Sibaii, Nermine N Mahfouz, Sara F Sallam, Reham F Fahmy, Azza Abd El-Shaheed

Open access · diamondAbstract read
In one paragraph

Article in Journal, genetic engineering & biotechnology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Salwa Refat El-ZayatMedical Physiology Department, National Research Centre, Medical Division, 33 El-Bohouth Street, Dokki POB:12311, Cairo, Egypt.
Hiba SibaiiMedical Physiology Department, National Research Centre, Medical Division, 33 El-Bohouth Street, Dokki POB:12311, Cairo, Egypt.
Nermine N MahfouzChild Health Department, National Research Centre, Medical Division, 33 El-Bohouth Street, Dokki, POB:12311, Cairo, Egypt.
Sara F SallamChild Health Department, National Research Centre, Medical Division, 33 El-Bohouth Street, Dokki, POB:12311, Cairo, Egypt.
Reham F FahmyChild Health Department, National Research Centre, Medical Division, 33 El-Bohouth Street, Dokki, POB:12311, Cairo, Egypt.
Azza Abd El-ShaheedChild Health Department, National Research Centre, Medical Division, 33 El-Bohouth Street, Dokki, POB:12311, Cairo, Egypt.
National Research Centre · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitamins are evaluated for their role in immunity. Recently, vitamin A received a particular attention as a critical micronutrient for regulating immune system. Therefore, the present study aimed to search for new about vitamin A. Forty-eight Egyptian adults aged from 18 to 42 years old from both sexes were subjected to clinical examination and nutrition questionnaire and were screened for vitamin A by using ELISA method. Forty subjects were selected and subdivided into two groups. Group 1 with vitamin A at level >200 µg/dl consists of 10 healthy subjects. Group 2 with vitamin A deficiency at level <50 µg/dl consists of 30 subjects. Tβ4 and CD4 levels were also determined by a commercial ELISA kit. Results showed a significant decrease in serum levels of Tβ4 and CD4 in group 2 than group 1 at P < .003 and P < .019 respectively. Both of Tβ4 and CD4 had positive correlation with vitamin A level at P < .000 and P < .003 respectively as well as with each other at p < .000. We concluded that vitamin A deficiency may be influence the levels of Tβ4 and CD4.

Indexed as

BMI, Body mass indexCBC, complete blood pictureCD4, cluster of differentiation 4cluster of differentiation (CD) 4Immune functionNRC, National Research CenterThymosin-β4 (Tβ4)Tβ4, Thymosin-β4VAD, vitamin A deficiencyVitamin A deficiency

Identifiers

PMID30647705
PMCPMC6296595
OpenAlexW2762018514

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.