Evidence map›Paper›PMID 30647682›Full record

ArticleJournal, genetic engineering & biotechnology2017

Serum apelin levels and metabolic risk markers in obese women.

Moushira Zaki, Sanaa Kamal, Wafaa Ezzat, Naglaa Hassan, Walaa Yousef, Hanaa Ryad, Ramy Mohamed, Eman Youness, Walaa Basha, Yasser Elhosary

Open access · diamondAbstract read
In one paragraph

Article in Journal, genetic engineering & biotechnology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 22 citations in OpenAlex.

  1. Comparative Effects ofNutrients · 2024
    Trial
  2. A Novel Marker in Hypogonadal Hypogonadism: Apelin.Sisli Etfal Hastanesi tip bulteni · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Obesity-Related Atrial Fibrillation: Cardiac Manifestation of a Systemic Disease.Journal of cardiovascular development and disease · 2023
    Review
  7. Review
  8. Correlation of serum apelin level with carotid intima-media thickness and insulin resistance in a sample of Egyptian patients with type 2 diabetes mellitus.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2022
    Article
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Moushira ZakiBiological Anthropology Department, Medical Research Division, Giza, Egypt.
Sanaa KamalBiological Anthropology Department, Medical Research Division, Giza, Egypt.
Wafaa EzzatInternal Medicine Department, Medical Research Division, Giza, Egypt.
Naglaa HassanBiological Anthropology Department, Medical Research Division, Giza, Egypt.
Walaa YousefBiological Anthropology Department, Medical Research Division, Giza, Egypt.
Hanaa RyadBiological Anthropology Department, Medical Research Division, Giza, Egypt.
Ramy MohamedBiological Anthropology Department, Medical Research Division, Giza, Egypt.
Eman YounessMedical Biochemistry Department, Medical Research Division, National Research Centre, Giza, Egypt.
Walaa BashaBiological Anthropology Department, Medical Research Division, Giza, Egypt.
Yasser ElhosaryInternal Medicine Department, Medical Research Division, Giza, Egypt.
Research Institute of Ophthalmology · EGNational Research Centre · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdipose tissue hormones, Adipokines, play an important role in obesity-associated complications. Apelin has recently been added to the family of adipokines. MATERIALS AND

methodsThe study included 400 unrelated women; they were 200 obese women and 200 non- obese matched healthy women. All participants underwent clinical, anthropometric and biochemical examinations. Insulin resistance (IR) was determined by the homeostasis model assessment of insulin resistance (HOMA-IR). Serum apelin levels and obesity biomarkers were measured using enzyme-linked immunoassay (ELISA) kits. Fat mass was measured by Tanita Body Composition Analyzer.

resultsObese women showed significant higher levels of serum apelin, leptin, triglycerides, LDL-C, total cholesterol, fasting insulin HOMA-IR and blood pressure levels than controls. Significant positive correlations between apelin and leptin levels with abnormal metabolic markers were noted in obese women.

conclusionThe present study suggests the significant role that might be mediated by apelin for developing abnormal metabolic parameters among Egyptian obese women.

Indexed as

HOMA-IRObeseSerum apelinWomen

Identifiers

PMID30647682
PMCPMC6296620
OpenAlexW2621931072

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.