ArticleThe ISME journal2019
Dual RNA-seq reveals large-scale non-conserved genotype × genotype-specific genetic reprograming and molecular crosstalk in the mycorrhizal symbiosis.
Article in The ISME journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 91 citations in OpenAlex.
- Linking Plant Metabolomics with Fungal Functional Dynamics Reveals a Noncanonical S-R-C Adaptive Trajectory.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Transcriptome Analysis of Arbuscular Mycorrhizal Fungi Using Short-Read Sequencing.Methods in molecular biology (Clifton, N.J.) · 2026Article
- Mycorrhizal control of microbial gene transcription and taxonomic composition in the rhizosphere and bulk soil.The ISME journal · 2025Article
- inDAGO: a user-friendly interface for seamless dual and bulk RNA-Seq analysis.Frontiers in bioinformatics · 2025Article
- Genotype-specific modulation of drought tolerance by arbuscular mycorrhizal symbiosis in foxtail millet.Frontiers in plant science · 2025Article
- A conserved fungal Knr4/Smi1 protein is crucial for maintaining cell wall stress tolerance and host plant pathogenesis.PLoS pathogens · 2025Article
- Dual RNA-Seq Reveals Temperature-Mediated Gene Reprogramming and Molecular Crosstalk between Grapevine andJournal of fungi (Basel, Switzerland) · 2023Article
- Differential Responses ofPlants (Basel, Switzerland) · 2023Article
- Variation of growth and transcriptome responses to arbuscular mycorrhizal symbiosis in different foxtail millet lines.Botanical studies · 2023Article
- Cross-tissue omics analysis discovers ten adipose genes encoding secreted proteins in obesity-related non-alcoholic fatty liver disease.EBioMedicine · 2023Article
- Ovarian transcriptional response to Wolbachia infection in D. melanogaster in the context of between-genotype variation in gene expression.G3 (Bethesda, Md.) · 2023Article
- Speciation Underpinned by Unexpected Molecular Diversity in the Mycorrhizal Fungal Genus Pisolithus.Molecular biology and evolution · 2023Article
- Synergetic effect of water deficit and arbuscular mycorrhizal symbiosis on the expression of aquaporins in wheat (Physiology and molecular biology of plants : an international journal of functional plant biology · 2023Article
- Stochastic nuclear organization and host-dependent allele contribution in Rhizophagus irregularis.BMC genomics · 2023Article
- Analysis of the molecular and biochemical mechanisms involved in the symbiotic relationship betweenFrontiers in plant science · 2023Article
- A roadmap to understanding diversity and function of coral reef-associated fungi.FEMS microbiology reviews · 2022Article
- Nutrition vs association: plant defenses are altered by arbuscular mycorrhizal fungi association not by nutritional provisioning alone.BMC plant biology · 2022Article
- RocTest: A standardized method to assess the performance of root organ cultures in the propagation of arbuscular mycorrhizal fungi.Frontiers in microbiology · 2022Article
- Symbiotic responses of Lotus japonicus to two isogenic lines of a mycorrhizal fungus differing in the presence/absence of an endobacterium.The Plant journal : for cell and molecular biology · 2021Article
- A historical perspective on mycorrhizal mutualism emphasizing arbuscular mycorrhizas and their emerging challenges.Mycorrhiza · 2021Review
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Arbuscular mycorrhizal fungi (AMF) impact plant growth and are a major driver of plant diversity and productivity. We quantified the contribution of intra-specific genetic variability in cassava (Manihot esculenta) and Rhizophagus irregularis to gene reprogramming in symbioses using dual RNA-sequencing. A large number of cassava genes exhibited altered transcriptional responses to the fungus but transcription of most of these plant genes (72%) responded in a different direction or magnitude depending on the plant genotype. Two AMF isolates displayed large differences in their transcription, but the direction and magnitude of the transcriptional responses for a large number of these genes was also strongly influenced by the genotype of the plant host. This indicates that unlike the highly conserved plant genes necessary for the symbiosis establishment, most of the plant and fungal gene transcriptional responses are not conserved and are greatly influenced by plant and fungal genetic differences, even at the within-species level. The transcriptional variability detected allowed us to identify an extensive gene network showing the interplay in plant-fungal reprogramming in the symbiosis. Key genes illustrated that the two organisms jointly program their cytoskeleton organization during growth of the fungus inside roots. Our study reveals that plant and fungal genetic variation has a strong role in shaping the genetic reprograming in response to symbiosis, indicating considerable genotype × genotype interactions in the mycorrhizal symbiosis. Such variation needs to be considered in order to understand the molecular mechanisms between AMF and their plant hosts in natural communities.
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