Evidence map›Paper›PMID 30646938›Full record

ArticleBMC research notes2019

High incidence of type III secretion system associated virulence factors (exoenzymes) in Pseudomonas aeruginosa isolated from Iranian burn patients.

Ramin Khodayary, Iraj Nikokar, Mohammad Reza Mobayen, Farhad Afrasiabi, Afshin Araghian, Ali Elmi, Meisam Moradzadeh

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In one paragraph

Article in BMC research notes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 12 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 12 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 12 syntheses or guidelines pooled it.

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  13. Correlation of type 3 secretion system genes with antimicrobial resistance inJournal of Taibah University Medical Sciences · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ramin KhodayaryDepartment of Microbiology, Faculty of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
Iraj NikokarDepartment of Microbiology, Faculty of Medicine, Guilan University of Medical Sciences, Rasht, Iran. nikokariraj@yahoo.com.
Mohammad Reza MobayenDepartment of Surgery, Guilan University of Medical Science, Rasht, Iran.
Farhad AfrasiabiDepartment of Microbiology, Faculty of Medicine, Guilan University of Medical Sciences, Rasht, Iran.
Afshin AraghianMedical Biotechnology Research Center, School of Paramedicine, Guilan University of Medical Sciences, Rasht, Iran.
Ali ElmiMedical Biotechnology Research Center, School of Paramedicine, Guilan University of Medical Sciences, Rasht, Iran.
Meisam MoradzadehDepartment of Microbiology, Faculty of Medicine, Guilan University of Medical Sciences, Rasht, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe present study aimed to determine the prevalence of virulence factors and antimicrobial resistance profile of Pseudomonas aeruginosa strains isolated from Iranian burn patients.

resultsThis cross-sectional study performed on 100 P. aeruginosa isolates which were recovered from burn wound specimens in 2014-2015. All presumptive isolates were identified by standard microbiologic tests. Antimicrobial susceptibility test was carried out by disk diffusion method. The presence of virulence genes was determined by PCR method. Antibiotic susceptibility results revealed that the isolates were mostly susceptible to amikacin (61%), ceftazidime (60%), and imipenem (55%). Moreover, 59% of the isolates were multi-drug resistance (MDR). The most prevalent MDR pattern was aminoglycosides-penicillins-fluoroquinolones-carbapenems (15%). The presence of exoT, exoY, exoS and exoU genes was detected in 100%, 100%, 59%, and 41% of the tested isolates, respectively. Results points out the pattern of MDR and genetic diversity of type III secretion system among P. aeruginosa strains isolated from the burn population. Overall, the association of MDR and the presence of the specific virulence genes can be a predictive marker for the persistence of these isolates in the hospitals and subsequently a worse clinical condition for the affected patients.

Indexed as

Anti-Bacterial AgentsBurn UnitsType III Secretion SystemsADP Ribose TransferasesBacterial ProteinsBacterial ToxinsBurnsCross-Sectional StudiesDrug Resistance, Multiple, BacterialGlucosyltransferasesGTPase-Activating ProteinsHumansIranMicrobial Sensitivity TestsPseudomonas aeruginosaVirulence FactorsADP Ribose TransferasesAnti-Bacterial AgentsBacterial ProteinsBacterial Toxinsexoenzyme SExoT protein, Pseudomonas aeruginosaExoY protein, bacteriaGlucosyltransferasesGTPase-Activating Proteinspseudomonas exoprotein A protein, Pseudomonas aeruginosaType III Secretion SystemsVirulence FactorsAntimicrobial resistanceBurn patientsPseudomonas aeruginosaType III secretion systemVirulence factors

Identifiers

PMID30646938
PMCPMC6334392

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.