Evidence map›Paper›PMID 30646598›Full record

ReviewGenes2019

Genomic Enhancers in Brain Health and Disease.

Nancy V N Carullo, Jeremy J Day

Abstract readReview
In one paragraph

Review in Genes, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Association of Intergenic and IntragenicInternational journal of molecular sciences · 2025
    Article
  6. Review
  7. Article
  8. AnFrontiers in genetics · 2025
    Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Nancy V N CarulloDepartment of Neurobiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA. ngallus@uab.edu.ORCID 0000-0001-9197-5046
Jeremy J DayDepartment of Neurobiology, University of Alabama at Birmingham, Birmingham, AL 35294, USA. jjday@uab.edu.ORCID 0000-0002-7361-3399

Funding

Epigenetic Control of Brain Reward SystemsDP1DA039650 · NIDA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI DAY, JEREMY J · 2015 to 2019
$2.3M
Enhancer RNA Regulation of Experience-dependent Neuroepigenetic ProcessesR01MH114990 · NIMH · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI DAY, JEREMY J · 2018 to 2022
$2.3M
Epigenetic Regulation of Cocaine-Induced NeuroadaptationsR00DA034681 · NIDA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI DAY, JEREMY J · 2014 to 2016
$741k
NIDA NIH HHS DP1 DA039650NIDA NIH HHS R00 DA034681NIMH NIH HHS R01 MH114990
6 · The paper itself

Abstract

Enhancers are non-coding DNA elements that function in

Indexed as

Enhancer Elements, GeneticAnimalsBrainBrain DiseasesHumansNeurogenesisenhancerepigeneticeRNAgene regulationneurontranscription

Identifiers

PMID30646598
PMCPMC6357130

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.