Evidence map›Paper›PMID 30646595›Full record

ArticleAntioxidants (Basel, Switzerland)2019

Relationship between Protein Oxidation Biomarkers and Uterine Health in Dairy Cows during the Postpartum Period.

Gianfranco Gabai, Elisabetta De Luca, Giovanni Miotto, Gianni Zin, Annalisa Stefani, Laura Da Dalt, Antonio Barberio, Pietro Celi

Open access · goldAbstract read
In one paragraph

Article in Antioxidants (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Gianfranco GabaiDepartment of Comparative Biomedicine and Food Science, University of Padova, 35020 Legnaro (PD), Italy. gianfranco.gabai@unipd.it.ORCID 0000-0001-9172-5127
Elisabetta De LucaDepartment of Comparative Biomedicine and Food Science, University of Padova, 35020 Legnaro (PD), Italy. dlelisabetta9@gmail.com.
Giovanni MiottoDepartment of Molecular Medicine, University of Padova, 35121 Padova, Italy. giovanni.miotto@unipd.it.
Gianni ZinVia Argine Sinistro 23 Creola di Saccolongo 35030 (PD), Italy. giannizin61@gmail.com.
Annalisa StefaniIstituto Zooprofilattico Sperimentale delle Venezie-Italian Health Authority and Research Organization for Animal Health and Food Safety, 35020Legnaro (PD), Italy. astefani@izsvenezie.it.ORCID 0000-0002-8071-0285
Laura Da DaltDepartment of Comparative Biomedicine and Food Science, University of Padova, 35020 Legnaro (PD), Italy. laura.dadalt@unipd.it.
Antonio BarberioIstituto Zooprofilattico Sperimentale delle Venezie-Italian Health Authority and Research Organization for Animal Health and Food Safety, 35020Legnaro (PD), Italy. abarberio@izsvenezie.it.ORCID 0000-0002-3108-8354
Pietro CeliDSM Nutritional Products, 4303 Kaiseraugst, Switzerland. pietro.celi@dsm.com.
University of Padua · ITIstituto Zooprofilattico Sperimentale delle Venezie · ITDSM (Switzerland) · CH

Funding

Italian Ministry of Education, University and Research PRIN prot. 2010YBP4LZ_002
6 · The paper itself

Abstract

High neutrophil (PMN, Polymorphonuclear neutrophil) counts in the endometrium of cows affected by endometritis, suggests the involvement of oxidative stress (OS) among the causes of impaired fertility. Protein oxidation, in particular, advanced oxidation protein products (AOPP), are OS biomarkers linked to PMN activity. To test this hypothesis, the relationship between protein oxidation and uterus health was studied in thirty-eight dairy cows during the puerperium. The animals were found to be cycling, without any signs of disease and pharmacological treatments. PMN count was performed either through a cytobrush or a uterine horn lavage (UHL). Cows were classified into four groups, based on the uterine ultrasonographic characteristics and the PMN percentage in the uterine horns with a higher percentage of high neutrophil horn (HNH). They were classified as: Healthy (H); Subclinical Endometritis (SCE); Grade 1 Endometritis (EM1); and Grade 2 Endometritis (EM2). AOPP and carbonyls were measured in plasma and UHL. UHL samples underwent Western blot analysis to visualize the carbonyl and dityrosine formation. Plasma AOPP were higher (

Indexed as

clinical outcomedairy cowoxidized proteinspuerperiumuterus

Identifiers

PMID30646595
PMCPMC6356478
OpenAlexW2910360013

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.