Evidence map›Paper›PMID 30646584›Full record

ReviewMolecules (Basel, Switzerland)2019

Alcyonacea: A Potential Source for Production of Nitrogen-Containing Metabolites.

Walied Mohamed Alarif, Ahmed Abdel-Lateff, Hajer Saeed Alorfi, Najla Ali Alburae

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Molecules (Basel, Switzerland) · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Walied Mohamed AlarifDepartment of Marine Chemistry, Faculty of Marine Sciences, King Abdulaziz University, PO. Box 80207, Jeddah 21589, Saudi Arabia. welaref@kau.edu.sa.
Ahmed Abdel-LateffDepartment of Natural Products and Alternative Medicine, Faculty of Pharmacy, King Abdulaziz University, PO Box 80260, Jeddah 21589, Saudi Arabia. aabdellatteff@kau.edu.sa.
Hajer Saeed AlorfiDepartment of Biology, Faculty of Science, King Abdulaziz University, PO. Box 80203, Jeddah 21589, Saudi Arabia. halorfi@kau.edu.sa.
Najla Ali AlburaeDepartment of Biology, Faculty of Science, King Abdulaziz University, PO. Box 80203, Jeddah 21589, Saudi Arabia. nalbourai@kau.edu.sa.ORCID 0000-0001-6331-7644

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alcyonacea (soft corals and gorgonia) are well known for their production of a wide array of unprecedented architecture of bioactive metabolites. This diversity of compounds reported from Alcyonacea confirms its productivity as a source of drug leads and, consequently, indicates requirement of further chemo-biological investigation. This review can be considered a roadmap to investigate the Alcyonacea, particularly those produce nitrogen-containing metabolites. It covers the era from the beginning of marine nitrogen-containing terpenoids isolation from Alcyonacea up to December 2018. One hundred twenty-one compounds with nitrogenous moiety are published from fifteen genera. Their prominent biological activity is evident in their antiproliferative effect, which makes them interesting as potential leads for antitumor agents. For instance, eleutherobin and sarcodictyins are in preclinical or clinical stages.

Indexed as

MetabolomeMetabolomicsAlkaloidsAnimalsAnthozoaCeramidesCerebrosidesDiterpenesMolecular StructureNitrogenProtein BindingTerpenesTubulinAlkaloidsCeramidesCerebrosidesDiterpenesNitrogenTerpenesTubulinAlcyonaceaantitumorcytotoxicityditerpenessesquiterpenes

Identifiers

PMID30646584
PMCPMC6359195

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.