Evidence map›Paper›PMID 30646485›Full record

ArticleJournal of neurogastroenterology and motility2019

Colonic Pseudo-obstruction With Transition Zone: A Peculiar Eastern Severe Dysmotility.

Eun Mi Song, Jong Wook Kim, Sun-Ho Lee, Kiju Chang, Sung Wook Hwang, Sang Hyoung Park, Dong-Hoon Yang, Kee Wook Jung, Byong Duk Ye, Jeong-Sik Byeon and 7 more

Open access · diamondAbstract read
In one paragraph

Article in Journal of neurogastroenterology and motility, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 1 country.

Eun Mi SongDepartments of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Jong Wook KimDepartment of Internal Medicine, Inje University Ilsan Paik Hospital, Goyang, Gyeonggi-do, Korea.
Sun-Ho LeeDepartments of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Kiju ChangDepartments of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Sung Wook HwangDepartments of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Sang Hyoung ParkDepartments of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Dong-Hoon YangDepartments of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Kee Wook JungDepartments of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Byong Duk YeDepartments of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Jeong-Sik ByeonDepartments of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Suk-Kyun YangDepartments of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Hyo Jeong LeeHealth Screening and Promotion Center, Asan Medical Center, Seoul, Korea.
Chang Sik YuDepartments of Colon and Rectal Surgery, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Chan Wook KimDepartments of Colon and Rectal Surgery, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Seong Ho ParkDepartments of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Jihun KimDepartments of Pathology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Seung-Jae MyungDepartments of Gastroenterology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
Ulsan College · KRUniversity of Ulsan · KRAsan Medical Center · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimsPrevious studies from Korea have described chronic intestinal pseudo-obstruction (CIPO) patients with transition zone (TZ) in the colon. In this study, we evaluated the pathological characteristics and their association with long-term outcomes in Korean colonic pseudo-obstruction (CPO) patients with TZ.

methodsWe enrolled 39 CPO patients who were refractory to medical treatment and underwent colectomy between November 1989 and April 2016 (median age at symptoms onset: 45 [interquartile range, 29-57] years, males 46.2%). The TZ was defined as a colonic segment connecting a proximally dilated and distally non-dilated segment. Detailed pathologic analysis was performed.

resultsAmong the 39 patients, 37 (94.9%) presented with TZ and 2 (5.1%) showed no definitive TZ. Median ganglion cell density in the TZ adjusted for the colonic circumference was significantly decreased compared to that in proximal dilated and distal non-dilated segments in TZ (+) patients (9.2 vs 254.3 and 150.5,

conclusionsHypoganglionosis can be identified in the TZ of most Korean CPO patients. Detection of other pathological features in addition to TZ-associated hypoganglionosis was associated with poor post-operative outcomes.

Indexed as

Colonic pseudo-obstructionIntestinal pseudo-obstructionOutcomesPathology

Identifiers

PMID30646485
PMCPMC6326194
OpenAlexW2910689554

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.