Evidence map›Paper›PMID 30645766›Full record

SynthesisCancer2019

Cancer disparities in people with HIV: A systematic review of screening for non-AIDS-defining malignancies.

Kelsey L Corrigan, Kevin C Wall, John A Bartlett, Gita Suneja

Open access · bronzeAbstract readSystematic Review
In one paragraph

Synthesis in Cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 39 citations in OpenAlex.

  1. Trial
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  8. Prostate Cancer Diagnosis Rates among Insured Men with and without HIV in South Africa: A Cohort Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2024
    Article
  9. Review
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  11. Review
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  14. Review
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  19. HIV-related lung cancer in Uganda: a cohort study.Infectious agents and cancer · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Kelsey L CorriganDuke University School of Medicine, Durham, North Carolina.ORCID 0000-0003-0314-6972
Kevin C WallDuke University School of Medicine, Durham, North Carolina.
John A BartlettDivision of Infectious Disease, Department of Medicine, Duke University Medical Center, Durham, North Carolina.
Gita SunejaDuke Global Health Institute, Durham, North Carolina.
Duke Institute for Health Innovation · USDuke University · US

Funding

Social and Behavioral Sciences CoreP30AI064518 · NIAID · DUKE UNIVERSITY · PI GEORGIA Doris TOMARAS · 2005 to 2026
$50.5M
Sociobehavioral Sciences Research to Improve Care for HIV Infection in TanzaniaD43TW009595 · FIC · KILIMANJARO CHRISTIAN MEDICAL CENTRE · PI Blandina Theophil Mmbaga · 2013 to 2026
$4.2M
Strengthening of Research Capacity for Junior Faculty in TanzaniaD43TW010138 · FIC · KILIMANJARO CHRISTIAN MEDICAL COLLEGE · PI MTETA, ALFRED KIEN · 2015 to 2020
$3.2M
Cancer Treatment Disparities in the HIV Population: Exploring the Impact of HIV on Physician and Patient Decision-MakingK08CA228631 · NCI · UNIVERSITY OF UTAH · PI SUNEJA, GITA · 2018 to 2022
$1.2M
FIC NIH HHS D43 TW009595FIC NIH HHS D43 TW010138NCI NIH HHS K08 CA228631NIAID NIH HHS P30 AI064518
6 · The paper itself

Abstract

backgroundPeople with HIV (PWHIV) have improved survival because of the advent of antiretroviral therapy. Consequently, PWHIV experience higher rates of non-acquired immunodeficiency syndrome-defining malignancies (NADMs). Previous studies have demonstrated worsened cancer-specific survival in PWHIV, partly because of advanced cancer stage at diagnosis. The objective of the current systematic review was to evaluate screening disparities for NADMs among PWHIV.

methodsThe PubMed, Cochrane, EMBASE, and ClinicalTrials.gov databases were searched from January 1, 1996 through April 10, 2018 to identify studies related to screening disparities for NADMs among PWHIV. Eligibility criteria included any study performed in a high-income country that compared screening for NADMs by HIV status. After title/abstract screening and full-text review, articles that met eligibility criteria were analyzed.

resultsOf 613 unique articles identified through the search, 9 studies were analyzed. Three studies addressed breast cancer screening, 4 addressed colorectal cancer screening, and 2 addressed prostate cancer screening. Five of the reviewed studies demonstrated that PWHIV were less likely to receive indicated cancer screenings compared with the general population, whereas 3 indicated that screening proportions were higher among PWHIV, and 1 demonstrated that screening proportions were comparable. In most of the studies, PWHIV who had regular access to health care were more likely to undergo cancer screening.

conclusionsThe available evidence does not uniformly confirm that PWHIV are less likely to receive cancer screening. Social determinants of health (insurance status, access to health care, education, income level) were associated with the receipt of appropriate cancer screening, suggesting that these barriers need to be addressed to improve cancer screening in PWHIV.

Indexed as

Breast NeoplasmsColorectal NeoplasmsEarly Detection of CancerFemaleHealthcare DisparitiesHIV InfectionsHumansMaleProstatic Neoplasmsacquired immunodeficiency syndromeearly detection of cancerhealth care disparitieshuman immunodeficiency virus (HIV)social determinants of health

Identifiers

PMID30645766
PMCPMC6488220
OpenAlexW2908994384

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.