Evidence map›Paper›PMID 30645677›Full record

ArticleMikrochimica acta2019

Yellow-emissive carbon dots with a large Stokes shift are viable fluorescent probes for detection and cellular imaging of silver ions and glutathione.

Fanyong Yan, Zhangjun Bai, Fanlin Zu, Yan Zhang, Xiaodong Sun, Tengchuang Ma, Liang Chen

Abstract read
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In one paragraph

Article in Mikrochimica acta, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
7.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 124 citations in OpenAlex.

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  19. WSMikrochimica acta · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Fanyong YanState Key Laboratory of Separation Membranes and Membrane Processes, Tianjin Engineering Center for Safety Evaluation of Water Quality & Safeguards Technology, College of Environmental and Chemical Engineering, Tianjin Polytechnic University, Tianjin, 300387, China. yanfanyong@tjpu.edu.cn.
Zhangjun BaiState Key Laboratory of Separation Membranes and Membrane Processes, Tianjin Engineering Center for Safety Evaluation of Water Quality & Safeguards Technology, College of Environmental and Chemical Engineering, Tianjin Polytechnic University, Tianjin, 300387, China.
Fanlin ZuState Key Laboratory of Separation Membranes and Membrane Processes, Tianjin Engineering Center for Safety Evaluation of Water Quality & Safeguards Technology, College of Environmental and Chemical Engineering, Tianjin Polytechnic University, Tianjin, 300387, China.
Yan ZhangState Key Laboratory of Separation Membranes and Membrane Processes, Tianjin Engineering Center for Safety Evaluation of Water Quality & Safeguards Technology, College of Environmental and Chemical Engineering, Tianjin Polytechnic University, Tianjin, 300387, China.
Xiaodong SunState Key Laboratory of Separation Membranes and Membrane Processes, Tianjin Engineering Center for Safety Evaluation of Water Quality & Safeguards Technology, College of Environmental and Chemical Engineering, Tianjin Polytechnic University, Tianjin, 300387, China.
Tengchuang MaDepartment of Nuclear Medicine, Harbin Medical University Cancer Hospital, Haping Road 150, Nangang District, Harbin City, 150081, Heilongjiang Province, China.
Liang ChenGraduate School of Life Science, Hokkaido University, Sapporo, 0010024, Japan.
Tianjin Polytechnic University · CNHarbin Medical University · CNHokkaido University · JP

Funding

National Natural Science Foundation of China 51678409, 51638011 and 51578375Program for Innovative Research Team in University of Tianjin TD13-5042State Key Laboratory of Separation Membranes and Membrane Processes Z1-201507Tianjin Research Program of Application Foundation and Advanced Technology 15ZCZDSF00880
6 · The paper itself

Abstract

Yellow-emissive carbon dots (Y-CDs) were prepared by a solvothermal method using anhydrous citric acid and 2,3-phenazinediamine as the starting materials. The Y-CDs display a 24% fluorescence quantum yield, a 188-nm Stokes' shift and excellent stability. They are shown here to be excellent fluorescent probes for the determination of Ag(I) ion and glutathione (GSH). If exposed to Ag(I) ions, they are bound by the carboxy groups of the Y-CDs, and this causes quenching of fluorescence (with excitation/emission maxima at 380/568 nm) via a static quenching mechanism. This effect was used to design a fluorometric assay for Ag(I). The quenched fluorescence of the Y-CDs can be restored by adding GSH due to the high affinity of GSH for Ag(I). The calibration plot for Ag(I) is linear in the 1-4 μM Ag(I) concentration range, and the limit of detection is 31 nM. The respective values for GSH are 5-32 μM, and 76 nM, respectively. The method was applied to the detection of Ag(I) in spiked environmental water samples and gave recoveries ranging from 93 to 107%. It was also applied to the determination of GSH in tomatoes and purple grapes and gave satisfactory recoveries. The Y-CDs display low cytotoxicity and were successfully used to image Ag(I) and GSH in H1299 cells. Graphical abstract Schematic presentation of the mechanism of yellow fluorescent CDs for the detection of Ag

Indexed as

Cell LineDiagnostic ImagingFluorescent DyesGlutathioneHumansIonsMicroscopy, FluorescenceMolecular ProbesSilverSolanum lycopersicumSpectrometry, FluorescenceVitisFluorescent DyesGlutathioneIonsMolecular ProbesSilverApplicationsFluorescence detectionFluorescence imagingFluorescence microscopyStern-Volmer plot

Identifiers

PMID30645677
OpenAlexW2910465261

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.