SynthesisPloS one2019
The value of vital sign trends in predicting and monitoring clinical deterioration: A systematic review.
Synthesis in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04674098 (The Effect of Real Time Analytics on Adverse Events Among Hospitalized Patients), which is not on this map. Cited by 116 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Real Time Analytics on Adverse Events Among Hospitalized Patients
Who cites it
116 citing papers in PubMed, 5 syntheses or guidelines pooled it, 306 citations in OpenAlex.
- Pooled it
- Machine learning techniques for mortality prediction in emergency departments: a systematic review.BMJ open · 2021Pooled it
- Pooled it
- A review of the literature on the accuracy, strengths, and limitations of visual, thoracic impedance, and electrocardiographic methods used to measure respiratory rate in hospitalized patients.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2021Pooled it
- Quantitative systematic review: Sources of inaccuracy in manually measured adult respiratory rate data.Journal of advanced nursing · 2021Pooled it
- Wearable Electronic Monitoring of Vital Signs in Hospitalised Adults: A Nursing Focused Scoping Review of Clinical, Economic and Implementation Outcomes.Journal of advanced nursing · 2026Article
- Portable Breathing Monitoring With Phase-Resolved Airflow Dynamics Enabled by a Dual-Response Flexible PZT Sensor.Advanced healthcare materials · 2026Article
- Towards generalizable contactless oximetry from multispectral video via deep domain-adaptive learning strategy.Biomedical optics express · 2026Article
- Assessing the Feasibility and Acceptability of Implementing a Preclinic Vital Signs Assessment in Primary Care: Cross-Sectional Pilot Study.JMIR medical informatics · 2026Article
- Process Improvement of In-Hospital Critical and Life-Threatening Patient Resuscitation: A Quality Improvement Project in a China Otolaryngology Hospital.Healthcare (Basel, Switzerland) · 2026Article
- Predicting Future Organ Support Needs Using Longitudinal Emergency Department Data: A Proof-of-Concept Study.Research square · 2026Article
- One Score Fits All? A Narrative Review on Early Warning Scores for Older Adults in the Emergency Department in the Era of Personalized Medicine.Journal of personalized medicine · 2026Review
- Immediate Effect of Whole-Body Vibration Exercise Performed in Vertical Versus Side-Alternating Displacement Modes on Physiological Parameters, Perception of Effort, Strength and Functionality in Adults with Obesity.Diagnostics (Basel, Switzerland) · 2026Article
- Vital signs as biomarkers of early clinical deterioration in pediatric emergency departments: physiology, interpretation, and innovations: a narrative review.International journal of emergency medicine · 2026Review
- Toward bidirectional FHIR-OMOP CDM transformations using TermX to support the secondary use of real-world health data within a patient-centered digital health paradigm.Frontiers in medicine · 2026Article
- Seamless vital sign monitoring with fiber optic sensing technology: validating the sitting SMART MAT for community health in static and mobile conditions.Frontiers in physiology · 2026Article
- Women's Occupational Tobacco Dust Exposure in Indonesia (T-CHARM): Protocol for a Prospective Cohort Study.JMIR research protocols · 2025Article
- Wearable Continuous Vital Sign Monitoring Study (WARD-AMS) to Detect Clinical Deterioration in Postoperative General Surgery Patients: Protocol for a Randomized Controlled Trial.JMIR research protocols · 2025Article
- Observational
- Smart emergency care: a narrative review of predictive machine learning models.Annals of translational medicine · 2025Review
56 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundVital signs, i.e. respiratory rate, oxygen saturation, pulse, blood pressure and temperature, are regarded as an essential part of monitoring hospitalized patients. Changes in vital signs prior to clinical deterioration are well documented and early detection of preventable outcomes is key to timely intervention. Despite their role in clinical practice, how to best monitor and interpret them is still unclear.
objectiveTo evaluate the ability of vital sign trends to predict clinical deterioration in patients hospitalized with acute illness. DATA SOURCES: PubMed, Embase, Cochrane Library and CINAHL were searched in December 2017. STUDY SELECTION: Studies examining intermittently monitored vital sign trends in acutely ill adult patients on hospital wards and in emergency departments. Outcomes representing clinical deterioration were of interest. DATA EXTRACTION: Performed separately by two authors using a preformed extraction sheet.
resultsOf 7,366 references screened, only two were eligible for inclusion. Both were retrospective cohort studies without controls. One examined the accuracy of different vital sign trend models using discrete-time survival analysis in 269,999 admissions. One included 44,531 medical admissions examining trend in Vitalpac Early Warning Score weighted vital signs. They stated that vital sign trends increased detection of clinical deterioration. Critical appraisal was performed using evaluation tools. The studies had moderate risk of bias, and a low certainty of evidence. Additionally, four studies examining trends in early warning scores, otherwise eligible for inclusion, were evaluated.
conclusionsThis review illustrates a lack of research in intermittently monitored vital sign trends. The included studies, although heterogeneous and imprecise, indicates an added value of trend analysis. This highlights the need for well-controlled trials to thoroughly assess the research question.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.