Evidence map›Paper›PMID 30645583›Full record

ArticlePloS one2019

Negative mood induction: Affective reactivity in recurrent, but not persistent depression.

Anne Guhn, Bruno Steinacher, Angela Merkl, Philipp Sterzer, Stephan Köhler

Erratum issuedAbstract read
In one paragraph

Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Feeling good, approaching the positive.Frontiers in psychology · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Anne GuhnDepartment of Psychiatry and Psychotherapy, Charité -Universitätsmedizin Berlin, Campus Mitte, Berlin, Germany.ORCID 0000-0003-1481-0269
Bruno SteinacherDepartment of Psychiatry and Psychotherapy, Vivantes GmbH Wenckebach-Hospital, Berlin, Germany.
Angela MerklDepartment of Psychiatry and Psychotherapy, Charité -Universitätsmedizin Berlin, Campus Mitte, Berlin, Germany.
Philipp SterzerDepartment of Psychiatry and Psychotherapy, Charité -Universitätsmedizin Berlin, Campus Mitte, Berlin, Germany.
Stephan KöhlerDepartment of Psychiatry and Psychotherapy, Charité -Universitätsmedizin Berlin, Campus Mitte, Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite the high clinical and epidemiological relevance of persistent depression, little is known about its specific psychopathology and whether it is distinct from recurrent depression. Depression in general has been associated with blunted affective reactivity but the evidence from previous studies is inconsistent. Here, we asked whether affective reactivity might differ between persistent and recurrent depression.

methodsTwenty patients with persistent depression, 20 patients with recurrent depression and 20 healthy controls (HC) were recruited. Both patient groups showed moderate symptom severity. All participants underwent a sad mood induction procedure. Affective reactivity was assessed with the Positive and Negative Affect Schedule (PANAS) before and after mood induction.

resultsWe found a striking difference in affective reactivity between patient groups. While the persistent group showed blunted reactivity to mood induction, the recurrent group demonstrated an affective response that was comparable to HC, with an increase in negative and a decrease in positive affect. Blunted affective reactivity was thus specifically associated with persistent in contrast to recurrent depression.

conclusionsThese results highlight affective reactivity as an important psychopathological feature that differs between the two patient groups. Preserved affective reactivity to emotional stimuli in the recurrent group might reflect a resilience factor against persistence of depression.

Indexed as

AdultAffectAntidepressive AgentsDepressionFemaleHumansMaleMiddle AgedRecurrenceAntidepressive Agents

Identifiers

PMID30645583
PMCPMC6333350

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