Evidence map›Paper›PMID 30645175›Full record

ArticleAmerican journal of physiology. Endocrinology and metabolism2019

Loss of

Yu Shao, Emily Wichern, Paul J Childress, Michele Adaway, Jagannath Misra, Angela Klunk, David B Burr, Ronald C Wek, Amber L Mosley, Yunlong Liu and 9 more

Open access · bronzeAbstract read
In one paragraph

Article in American journal of physiology. Endocrinology and metabolism, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Review
  7. Conditional Loss of Nmp4 in Mesenchymal Stem Progenitor Cells Enhances PTH-Induced Bone Formation.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2023
    Article
  8. Article
  9. Article
  10. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 4 institutions in 1 country.

Yu ShaoDepartment of Medical and Molecular Genetics, Indiana University School of Medicine , Indianapolis, Indiana.
Emily WichernDepartment of Anatomy and Cell Biology, Indiana University School of Medicine , Indianapolis, Indiana.
Paul J ChildressDepartment of Orthopaedic Surgery, Indiana University School of Medicine , Indianapolis, Indiana.
Michele AdawayDepartment of Anatomy and Cell Biology, Indiana University School of Medicine , Indianapolis, Indiana.
Jagannath MisraDepartment of Biochemistry and Molecular Biology, Indiana University School of Medicine , Indianapolis, Indiana.
Angela KlunkDepartment of Anatomy and Cell Biology, Indiana University School of Medicine , Indianapolis, Indiana.
David B BurrDepartment of Anatomy and Cell Biology, Indiana University School of Medicine , Indianapolis, Indiana.
Ronald C WekDepartment of Biochemistry and Molecular Biology, Indiana University School of Medicine , Indianapolis, Indiana.
Amber L MosleyDepartment of Biochemistry and Molecular Biology, Indiana University School of Medicine , Indianapolis, Indiana.
Yunlong LiuDepartment of Medical and Molecular Genetics, Indiana University School of Medicine , Indianapolis, Indiana.
Alexander G RoblingDepartment of Anatomy and Cell Biology, Indiana University School of Medicine , Indianapolis, Indiana.
Nickolay BrustovetskyDepartment of Pharmacology and Toxicology, Indiana University School of Medicine , Indianapolis, Indiana.
James HamiltonDepartment of Pharmacology and Toxicology, Indiana University School of Medicine , Indianapolis, Indiana.
Kylie JacobsDepartment of Microbiology and Immunology, Indiana University School of Medicine , Indianapolis, Indiana.
Deepak VashishthCenter for Biotechnology and Interdisciplinary Studies and Department of Biomedical Engineering, Rensselaer Polytechnic Institute , Troy, New York.
Keith R StayrookLilly Research Laboratories, Eli Lilly and Company , Indianapolis, Indiana.
Matthew R AllenDepartment of Anatomy and Cell Biology, Indiana University School of Medicine , Indianapolis, Indiana.
Joseph M WallaceDepartment of Orthopaedic Surgery, Indiana University School of Medicine , Indianapolis, Indiana.
Joseph P BidwellDepartment of Medical and Molecular Genetics, Indiana University School of Medicine , Indianapolis, Indiana.
Indiana University – Purdue University Indianapolis · USIndiana University School of MedicineEli Lilly (United States) · USRensselaer Polytechnic Institute · US

Funding

Translation CoreP30DK097512 · NIDDK · INDIANA UNIVERSITY INDIANAPOLIS · PI Carmella Evans-Molina · 2015 to 2026
$17.4M
Lrp5 signaling in bone mechanotransduction and metabolismR01AR053237 · NIAMS · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI ALEXANDER G ROBLING, Matthew L Warman · 2005 to 2026
$9.4M
Metabolic stress responses andeIF2 kinase GCN2R01GM049164 · NIGMS · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI WEK, RONALD C · 1998 to 2019
$6.3M
CRMP2, mitochondria, and Huntington’s diseaseR01NS098772 · NINDS · INDIANA UNIVERSITY INDIANAPOLIS · PI BRUSTOVETSKY, NICKOLAY, KHANNA, RAJESH · 2017 to 2021
$2.8M
Enhancing bone strength using combination drug therapyR01AR062002 · NIAMS · INDIANA UNIVERSITY INDIANAPOLIS · PI ALLEN, MATTHEW R · 2012 to 2016
$2.4M
The Nmp4 Anti-Anabolic Bone Axis R01AR070144-01A1R01AR073739 · NIAMS · INDIANA UNIVERSITY INDIANAPOLIS · PI BIDWELL, JOSEPH P · 2018 to 2022
$2.0M
Mechanical Protection of Pathological Collagen SynthesisK25AR067221 · NIAMS · INDIANA UNIVERSITY INDIANAPOLIS · PI WALLACE, JOSEPH MICHAEL · 2015 to 2017
$419k
Lrp5 and Lrp6 signaling in bone mechanotransduction and metabolismR56AR053237 · NIAMS · INDIANA UNIVERSITY INDIANAPOLIS · PI ROBLING, ALEXANDER G, WARMAN, MATTHEW L · 2023 to 2023
$349k
NIAMS NIH HHS K25 AR067221NIAMS NIH HHS R01 AR053237NIAMS NIH HHS R01 AR062002NIAMS NIH HHS R01 AR073739NIAMS NIH HHS R56 AR053237NIDDK NIH HHS P30 DK097512NIGMS NIH HHS R01 GM049164NINDS NIH HHS R01 NS098772
6 · The paper itself

Abstract

A goal of osteoporosis therapy is to restore lost bone with structurally sound tissue. Mice lacking the transcription factor nuclear matrix protein 4 (

Indexed as

AnimalsBone MatrixCalcification, PhysiologicCollagenGene Expression ProfilingGene Expression RegulationGlycolysisMesenchymal Stem CellsMiceMice, KnockoutNuclear Matrix-Associated ProteinsOsteoblastsOsteogenesisOsteoporosisRNA, MessengerTranscription FactorsCollagenNuclear Matrix-Associated ProteinsRNA, MessengerTranscription FactorsZfp384 protein, mousebone biomechanicsmetabolismosteoporosisparathyroid hormonetranscriptome

Identifiers

PMID30645175
PMCPMC6580174
OpenAlexW2910033131

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.