Evidence map›Paper›PMID 30644627›Full record

Trial reportAddiction (Abingdon, England)2019

Vaping characteristics and expectancies are associated with smoking cessation propensity among dual users of combustible and electronic cigarettes.

Karen O Brandon, Vani N Simmons, Lauren R Meltzer, David J Drobes, Úrsula Martínez, Steven K Sutton, Amanda M Palmer, Christopher R Bullen, Paul T Harrell, Thomas H Brandon

Open access · greenAbstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Addiction (Abingdon, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 22 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Karen O BrandonDepartment of Health Outcomes and Behavior, H. Lee Moffitt Cancer Center, Tampa, FL, USA.ORCID 0000-0003-3948-5650
Vani N SimmonsDepartment of Health Outcomes and Behavior, H. Lee Moffitt Cancer Center, Tampa, FL, USA.
Lauren R MeltzerDepartment of Health Outcomes and Behavior, H. Lee Moffitt Cancer Center, Tampa, FL, USA.
David J DrobesDepartment of Health Outcomes and Behavior, H. Lee Moffitt Cancer Center, Tampa, FL, USA.
Úrsula MartínezDepartment of Health Outcomes and Behavior, H. Lee Moffitt Cancer Center, Tampa, FL, USA.
Steven K SuttonDepartment of Psychology, University of South Florida, Tampa, FL, USA.
Amanda M PalmerDepartment of Health Outcomes and Behavior, H. Lee Moffitt Cancer Center, Tampa, FL, USA.
Christopher R BullenSchool of Population Health, Faculty of Medical and Health Science, University of Auckland, New Zealand.
Paul T HarrellDepartment of Pediatrics, Eastern Virginia Medical School, Norfolk, VA, USA.
Thomas H BrandonDepartment of Health Outcomes and Behavior, H. Lee Moffitt Cancer Center, Tampa, FL, USA.
University of South Florida · USMoffitt Cancer Center · USEastern Virginia Medical School · USUniversity of Auckland · NZ

Funding

TRANSLATIONAL RESEARCHP30CA076292 · NCI · UNIVERSITY OF SOUTH FLORIDA · PI John L. Cleveland · 1998 to 2026
$93.5M
Smoking Cessation Self-Help for Dual Users of Tobacco Cigarettes and E-CigarettesR01DA037961 · NIDA · H. LEE MOFFITT CANCER CTR & RES INST · PI BRANDON, THOMAS H · 2015 to 2019
$3.7M
NCI NIH HHS P30 CA076292NIDA NIH HHS R01 DA037961
6 · The paper itself

Abstract

BACKGROUND AND

aimsMost e-cigarette users who also smoke combustible cigarettes (dual users) begin vaping to quit smoking, yet only a subset succeeds. We hypothesized that reinforcing characteristics of e-cigarettes (vaping reinforcement) would positively predict smoking cessation propensity (SCP) among dual users.

designSecondary analysis of cross-sectional baseline data from dual users in an ongoing smoking cessation trial. Exploratory and confirmatory factor analysis (EFA and CFA) created latent variables for vaping reinforcement and SCP. A structural equation modeling (SEM) approach was used to test the hypothesis.

settingUnited States.

participantsA national sample of dual users of combustible and electronic cigarettes who smoke and vape at least once per week (n = 2896) were enrolled (63% male; mean age = 29.9 years) into a randomized controlled trial in which they would receive either smoking cessation materials or no smoking cessation materials. MEASUREMENTS: Vaping reinforcement was indexed by vaping frequency (days/week vaping, times/day vaping, puffs/e-cigarette use), e-cigarette characteristics [numbers of modifications and tobacco or non-tobacco flavors, nicotine content (mg) and positive e-cigarette expectancies]. SCP was measured by items of confidence, commitment to being smoke-free, cessation motivation (contemplation ladder), change in cigarettes per day since beginning e-cigarette use and negative smoking expectancies.

findingsFour factors emerged from the EFA: vaping propensity (vaping frequency, positive expectancies), vaping enthusiasm (e-cigarette modifications, using non-tobacco flavors, puffs per use), nicotine/tobacco flavor (nicotine strength, tobacco flavors) and SCP (negative expectancies about smoking, motivation to quit smoking, reduction in smoking). A CFA upheld the exploratory factor structure [root mean square error of approximation (RMSEA) = 0.046, CFI = 0.91]. An SEM with the three vaping latent variables directly predicting SCP had good model fit (RMSEA = 0.030, CFI = 0.97) with a positive relationship of vaping propensity (0.509, P < 0.001), and small negative relationships of vaping enthusiasm (-0.158, P = 0.014) and nicotine/tobacco flavor (-0.230, P < 0.001).

conclusionsAmong e-cigarette users who also smoke combustible cigarettes, frequent vaping combined with positive e-cigarette expectancies appears to predict greater smoking cessation propensity. However, vaping enthusiasm (measured by e-cigarette modifications, using non-tobacco flavors and puffs per use), higher nicotine content and use of tobacco flavored solution may reduce cessation propensity.

Indexed as

Electronic Nicotine Delivery SystemsMotivationAdultFemaleHumansLatent Class AnalysisMalePropensity ScoreSmoking CessationVapingDual-usee-cigaretteslatent variablesmokingsmoking cessationstructural equation modeling

Identifiers

PMID30644627
PMCPMC6629519
OpenAlexW2908591930

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.