Evidence map›Paper›PMID 30644556›Full record

ReviewAnnals of the New York Academy of Sciences2020

Are low-carbohydrate diets safe in diabetic and nondiabetic chronic kidney disease?

Nia S Mitchell, Julia J Scialla, William S Yancy

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Annals of the New York Academy of Sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05350657 (Ketogenic Dietary Patterns in Young Adults and Kidney Health), which is not on this map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05350657 naterminatednot on this mapstarted 2022, after this paper: background citation

Ketogenic Dietary Patterns in Young Adults and Kidney Health

TypeinterventionalSponsorUniversity of VirginiaRan2022 to 2023Enrolled5ConditionsKetogenic Diet, Kidney InjuryArmsKetogenic Diet
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. Does a Ketogenic Diet Have a Place Within Diabetes Clinical Practice? Review of Current Evidence and Controversies.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2024
    Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Nia S MitchellDivision of General Internal Medicine, Department of Medicine, Duke University School of Medicine, Durham, North Carolina.
Julia J SciallaDivision of Nephrology, Department of Medicine, Duke University School of Medicine, Durham, North Carolina.
William S YancyDivision of General Internal Medicine, Department of Medicine, Duke University School of Medicine, Durham, North Carolina.
Duke University · USDuke University Health System · US

Funding

Integrated Mineral Metabolism Treatment Strategies in Patients on DialysisR01DK111952 · NIDDK · UNIVERSITY OF VIRGINIA · PI SCIALLA, JULIA J · 2017 to 2020
$1.6M
Evaluation of Low Cost National Weight Loss Program in the UnderservedK01HL115599 · NHLBI · UNIVERSITY OF COLORADO DENVER · PI MITCHELL, NIA SCHWANN · 2012 to 2016
$718k
NHLBI NIH HHS K01 HL115599NIDDK NIH HHS R01 DK111952
6 · The paper itself

Abstract

Diabetes mellitus and obesity both contribute to chronic kidney disease (CKD) and diabetic kidney disease (DKD), and they can accelerate the loss of kidney function. Dietary intake can potentially have wide-reaching effects on the risk of CKD/DKD and their progression by reducing weight and blood pressure, improving glycemic control, reducing hyperfiltration, and modulating inflammation. Low-carbohydrate (LC) diets can reduce weight and improve glycemic control, but the relatively higher protein content also raises concern in CKD/DKD. Empiric evidence supporting the kidney-related benefits or risks of LC diets is needed to understand the balance of these potential harms and benefits for patients with DKD and is the subject of our review.

Indexed as

Diet, Carbohydrate-RestrictedDiabetic NephropathiesDietary ProteinsGuidelines as TopicHumansObesityRenal Insufficiency, ChronicDietary Proteinschronic kidney diseasediabetic kidney diseaselow-carbohydrate diets

Identifiers

PMID30644556
PMCPMC6629514
OpenAlexW2908620359

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.