Evidence map›Paper›PMID 30644365›Full record

ArticleDiagnostic and interventional radiology (Ankara, Turkey)2019

Discrimination of oncocytoma and chromophobe renal cell carcinoma using MRI.

Işıl Başara Akın, Canan Altay, Ezgi Güler, İlkay Çamlıdağ, Mustafa Harman, Murat Danacı, Burçin Tuna, Kutsal Yörükoğlu, Mustafa Seçil

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Diagnostic and interventional radiology (Ankara, Turkey), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 30 citations in OpenAlex.

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  16. Chromophobe Renal Cell Carcinoma with Radiologic-Pathologic Correlation.Radiographics : a review publication of the Radiological Society of North America, Inc
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Işıl Başara AkınDepartment of Radiology, Dokuz Eylül University School of Medicine, İzmir, Turkey.
Canan AltayDepartment of Radiology, Dokuz Eylül University School of Medicine, İzmir, Turkey.
Ezgi GülerDepartment of Radiology, Ege University School of Medicine, İzmir, Turkey.
İlkay ÇamlıdağDepartment of Radiology, Ondokuz Mayıs University School of Medicine, Samsun, Turkey.
Mustafa HarmanDepartment of Radiology, Ege University School of Medicine, İzmir, Turkey.
Murat DanacıDepartment of Radiology, Ondokuz Mayıs University School of Medicine, Samsun, Turkey.
Burçin TunaDepartment of Pathology, Dokuz Eylul University School of Medicine, İzmir, Turkey.
Kutsal YörükoğluDepartment of Pathology, Dokuz Eylul University School of Medicine, İzmir, Turkey.
Mustafa SeçilDepartment of Radiology, Dokuz Eylül University School of Medicine, İzmir, Turkey.
Ege University · TRDokuz Eylül University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeWe aimed to evaluate magnetic resonance imaging (MRI) features, including signal intensities, enhancement patterns and T2 signal intensity ratios to differentiate oncocytoma from chromophobe renal cell carcinoma (RCC).

methodsThis retrospective study included 17 patients with oncocytoma and 33 patients with chromophobe RCC who underwent dynamic MRI. Two radiologists independently reviewed images blinded to pathology. Morphologic characteristics, T1 and T2 signal intensities were reviewed. T2 signal intensities, wash-in, wash-out values, T2 signal intensity ratios were calculated. Sensitivity and specificity analyses were performed.

resultsMean ages of patients with oncocytoma and chromophobe RCC were 61.0±11.6 and 58.5±14.0 years, respectively. Mean tumor size was 60.6±47.3 mm for oncocytoma, 61.7±45.9 mm for chromophobe RCC. Qualitative imaging findings in conventional MRI have no distinctive feature in discrimination of two tumors. Regarding signal intensity ratios, oncocytomas were higher than chromophobe RCCs. Renal oncocytomas showed higher signal intensity ratios and wash-in values than chromophobe RCCs in all phases. Fast spin-echo T2 signal intensities were higher in oncocytomas than chromophobe RCCs.

conclusionSignal intensity ratios, fast spin-echo T2 signal intensities and wash-in values constitute diagnostic parameters for discriminating between oncoytomas and chromophobes. In the excretory phase of dynamic enhanced images, oncocytomas have higher signal intensity ratio than chromophobe RCC and high wash-in values strongly imply a diagnosis of renal oncocytoma.

Indexed as

Adenoma, OxyphilicAdultAgedCarcinoma, Renal CellDiagnosis, DifferentialFemaleHumansImage EnhancementKidney NeoplasmsMagnetic Resonance ImagingMaleMiddle AgedRetrospective StudiesSensitivity and Specificity

Identifiers

PMID30644365
PMCPMC6339620
OpenAlexW2908526393

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.