ReviewIndian journal of pediatrics2019
Does India Need a Universal High-Dose Vitamin A Supplementation Program?
Review in Indian journal of pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Trial
- Expansion of The ABCA4-Associated Retinopathy Spectrum: Might Vitamin A Supplementation Have Contributed to a More Severe Phenotype?Investigative ophthalmology & visual science · 2025Article
- Exploring a spatial template for targetted supplementation of vitamin A in under-5 Indian children.Pediatric research · 2023Article
- Vitamin A supplementation among 9-59 month old children in India: geospatial perspectives and implications for targeted coverage.BMJ global health · 2022Article
- Dietary diversity as a sustainable approach towards micronutrient deficiencies in India.The Indian journal of medical research · 2022Review
- Vitamin A supplementation and estimated number of averted child deaths in Ethiopia: 15 years in practice (2005-2019).Maternal & child nutrition · 2021Article
- Perspective: Integration to Implementation (I-to-I) and the Micronutrient Forum-Addressing the Safety and Effectiveness of Vitamin A Supplementation.Advances in nutrition (Bethesda, Md.) · 2020Article
- Rubella Virus Infection, the Congenital Rubella Syndrome, and the Link to Autism.International journal of environmental research and public health · 2019Review
- Child Health Policies in India: Moving from a Discernible Past to a Promising Future.Indian journal of pediatrics · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
High dose vitamin A (HDVA) concentrate began to be distributed in India in 1970 as a short-term, stop-gap approach to reduce clinical signs of vitamin A deficiency. As this problem declined globally, the purpose of distributing them changed to the reduction of young child mortality. However, their impact on this has also declined, if not disappeared, as suggested in India by the enormous DEVTA study. This may be because of improved protection against and treatment of the main morbidity involved, measles and diarrhea. At the same time, semi-annual provision of mega-doses of vitamin A is not without risks, in particular linked to children's vaccination status. While a single dose is inexpensive, large-scale implementation of HDVA programs is expensive, particularly the opportunity cost involved in reducing the time health workers involved have to deal with their other commitments. Balancing potential benefits, risks and costs leads us to recommend an immediate cessation of the distribution of HDVA in India.
Indexed as
Identifiers
30644040What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.