ArticleEuropean radiology2019
The usefulness of cardiac CT in the diagnosis of perivalvular complications in patients with infective endocarditis.
Article in European radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.
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Who cites it
40 citing papers in PubMed, 1 synthesis or guideline pooled it, 74 citations in OpenAlex.
- Quality assessment of radiomics research in cardiac CT: a systematic review.European radiology · 2022Pooled it
- The diagnostic value of additional ECG-gated CT for the diagnosis of aortic valve endocarditis with aortic root abscesses and pseudoaneurysms: A comparison with transoesophageal echocardiography and intraoperative findings.The international journal of cardiovascular imaging · 2026Article
- Current Surgical Approaches to Managing Infective Endocarditis With Aortic Root Abscess.Reviews in cardiovascular medicine · 2026Review
- Infective Endocarditis: A Contemporary Review of Epidemiology, Diagnosis, and Management.Antibiotics (Basel, Switzerland) · 2026Review
- Echocardiographically occult nonbacterial thrombotic endocarditis with tumor cell-containing valvular vegetations in metastatic breast cancer.Cardio-oncology (London, England) · 2026Article
- Mitral-Aortic Intervalvular Fibrosa Pseudoaneurysm: A Rare and Life-Threatening Presentation.Cureus · 2026Article
- The Biological Cost of Every Heartbeat: Imaging-Derived Cardiovascular Vulnerability in Infective Endocarditis.International journal of molecular sciences · 2026Article
- Current Advances in Epidemiology, Diagnosis, and Management of TAVR-Associated Infective Endocarditis: A Narrative Review.Reviews in cardiovascular medicine · 2026Review
- Enhancing Surgical Decision-Making for Infected Cardiac Device Lead Removal With 18F-FDG PET/CT: A Case Study and Literature Analysis.Clinical case reports · 2026Article
- Post-operative infection treatment in cardiac surgery: current practices and future directions.Perioperative medicine (London, England) · 2025Review
- A multimodality imaging approach to the diagnosis of infective endocarditis: incremental value of combining modalities.The international journal of cardiovascular imaging · 2025Review
- Percutaneous Closure of Perivalvular Leakage After Aortic Valve Replacement Using Preoperative 3D Printing Technology Guidance: A Case Report.Clinical case reports · 2025Article
- Change of Heart: Can Artificial Intelligence Transform Infective Endocarditis Management?Pathogens (Basel, Switzerland) · 2025Review
- Comprehensive CT study to assess local and systemic involvement in patients with infective endocarditis: experience from a multidisciplinary team of a tertiary referral center.La Radiologia medica · 2025Article
- The role of multimodality imaging in calcified valves with infective endocarditis.Journal of geriatric cardiology : JGC · 2024Article
- Infective Endocarditis in Patients with End-Stage Renal Disease on Dialysis: Epidemiology, Risk Factors, Diagnostic Challenges, and Management Approaches.Healthcare (Basel, Switzerland) · 2024Review
- Imaging in Infective Endocarditis-Current Opinions and Trends in Cardiac Computed Tomography.Diagnostics (Basel, Switzerland) · 2024Review
- Cardiac computed tomography in infective endocarditis: "bridging the detection gap".Frontiers in cardiovascular medicine · 2024Review
- Importance of experience in transoesophageal echocardiographic evaluation of vegetation size in patients with infective endocarditis: a reliability study.European heart journal. Imaging methods and practice · 2024Article
- Multimodality Imaging Diagnosis in Infective Endocarditis.Life (Basel, Switzerland) · 2023Review
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe aim of the study was to compare the usefulness of cardiac CT to transthoracic (TTE) and transesophageal (TEE) echocardiography in the diagnosis of infective endocarditis (IE) and perivalvular complications using surgical inspection as the gold standard. MATERIAL AND
methodsFifty-three consecutive patients (42 men, mean age 58.3 ± 12.5) with IE requiring surgical procedures were enrolled in the study. All patients underwent preoperative TTE, TEE, and CT. The presence of vegetations, perivalvular abscess/pseudoaneurysm, leaflet perforation, inflammatory infiltration, and prosthesis dehiscence was assessed.
resultsWe analyzed 71 affected valves (58 native, 13 prosthetic). Intraoperative assessment revealed 11 abscesses/pseudoaneurysms. Sensitivity and specificity of echocardiography (TTE + TEE) and CT were 63%, 90% and 81%, 90%, respectively. The combination of CT and echocardiography allowed diagnosing all abscesses/pseudoaneurysms. Inflammatory infiltration was found intraoperatively in 15 patients. Sensitivity and specificity of TEE and CT were 53%, 94% and 46%, 100%, respectively. Intraoperative assessment revealed leaflet perforation in 16 patients. Sensitivity and specificity of TEE and CT were 75%, 79% and 43%, 89%. The sensitivity of the combination of TTE + TEE + CT was 81%. Perivalvular leakage was found in eight patients with a prosthetic valve. Sensitivity and specificity of echocardiography and CT were 100%, 100% and 88%, 100%, respectively. TEE showed higher sensitivity (97%) than CT (89%) in the diagnosis of vegetations.
conclusionsThe combination of TTE, TEE, and CT increased the sensitivity for the detection of valvular and perivalvular complications of IE. KEY POINTS: • CT is a useful modality in the diagnosis of IE and its local complications in addition to echocardiography. • For the detection of abscesses and pseudoaneurysms, CT is superior to echocardiography. Combining these two modalities can increase the sensitivity of diagnosing abscess/pseudoaneurysm up to 100%. • Adding CT to TEE increases the sensitivity for detection of inflammatory infiltrate. CT is not superior to echocardiography in diagnosing vegetations, valvular leaflet perforations, and perivalvular leaks, but it can be a useful tool when echocardiography is indeterminate.
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