Evidence map›Paper›PMID 30643897›Full record

ArticleMicrobiology resource announcements2019

High-Depth RNA-Seq Data Sets for Studying Gene Expression Changes Mediated by Phase-Variable DNA Methyltransferases in Nontypeable Haemophilus influenzae.

John M Atack, Lauren O Bakaletz, Michael P Jennings

Open access · diamondAbstract read
In one paragraph

Article in Microbiology resource announcements, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Panel 1: Biotechnology, biomedical engineering and new models of otitis media.International journal of pediatric otorhinolaryngology · 2020
    Review
  2. A Bacterial Epigenetic Switch in Non-typeableFrontiers in cellular and infection microbiology · 2020
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

John M AtackInstitute for Glycomics, Griffith University, Gold Coast, Queensland, Australia.ORCID https://orcid.org/0000-0002-7994-6995
Lauren O BakaletzCenter for Microbial Pathogenesis, The Research Institute at Nationwide Children's Hospital and The Ohio State University College of Medicine, Columbus, Ohio, USA.
Michael P JenningsInstitute for Glycomics, Griffith University, Gold Coast, Queensland, Australia.
Griffith University · AUNationwide Children's Hospital · US

Funding

Otitis media: role of epigenetic regulation on NTHI pathogenesis and optimal vaccine designR01DC015688 · NIDCD · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI BAKALETZ, LAUREN O, JENNINGS, MICHAEL PAUL · 2016 to 2020
$2.2M
NIDCD NIH HHS R01 DC015688
6 · The paper itself

Abstract

Nontypeable Haemophilus influenzae (NTHi) is a major bacterial pathogen that causes multiple infections. We report high-depth-coverage RNA-Seq data from three NTHi strains, each of which encodes a different phase-variable methyltransferase. Major gene expression differences occur, commensurate with

Identifiers

PMID30643897
PMCPMC6328670
OpenAlexW2909800520

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.