Evidence map›Paper›PMID 30643813›Full record

ArticleBioMed research international2018

Impact of Matrix Metalloproteinase 9 on COPD Development in Polish Patients: Genetic Polymorphism, Protein Level, and Their Relationship with Lung Function.

Iwona Gilowska, Łukasz Kasper, Katarzyna Bogacz, Jan Szczegielniak, Teresa Szymasek, Marta Kasper, Marcin Czerwinski, Krzysztof Sładek, Edyta Majorczyk

Open access · hybridAbstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BioMed research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Observational
  5. Article
  6. Association of theArchives of medical science : AMS · 2024
    Review
  7. UnripeNutrients · 2023
    Article
  8. TIMP-1 and its potential diagnostic and prognostic value in pulmonary diseases.Chinese medical journal pulmonary and critical care medicine · 2023
    Article
  9. Observational
  10. Matrix Metalloproteinases in Chronic Obstructive Pulmonary Disease.International journal of molecular sciences · 2023
    Review
  11. Excessive Facial Wrinkling Is Associated with COPD Occurrence-Does COPD Damage Skin Beauty and Quality?International journal of environmental research and public health · 2023
    Article
  12. Article
  13. A2M Serves as Promising Biomarker for Chronic Obstructive Pulmonary Disease.International journal of chronic obstructive pulmonary disease · 2023
    Article
  14. Antioxidants (Basel, Switzerland) · 2022
    Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Iwona GilowskaInstitute of Physiotherapy, Faculty of Physical Education and Physiotherapy, Opole University of Technology, Opole, Poland.
Łukasz KasperSecond Department of Internal Medicine, Department of Pulmonology, Collegium Medicum, Jagiellonian University in Cracow Kraków, Poland.
Katarzyna BogaczInstitute of Physiotherapy, Faculty of Physical Education and Physiotherapy, Opole University of Technology, Opole, Poland.
Jan SzczegielniakInstitute of Physiotherapy, Faculty of Physical Education and Physiotherapy, Opole University of Technology, Opole, Poland.
Teresa SzymasekDepartment of Pulmonology, Opole Voivodship Hospital, Opole, Poland.
Marta KasperFaculty of Health Sciences, Jagiellonian University Medical College, Krakow, Poland.
Marcin CzerwinskiInstitute of Physiotherapy, Faculty of Physical Education and Physiotherapy, Opole University of Technology, Opole, Poland.
Krzysztof SładekSecond Department of Internal Medicine, Department of Pulmonology, Collegium Medicum, Jagiellonian University in Cracow Kraków, Poland.
Edyta MajorczykInstitute of Physiotherapy, Faculty of Physical Education and Physiotherapy, Opole University of Technology, Opole, Poland.ORCID 0000-0001-7248-9544
Opole University of Technology · PLJagiellonian University · PLPublic Higher Medical Professional School in Opole · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic obstructive pulmonary disease (COPD) is characterized by a decline of lung function and symptoms such as chronic bronchitis and emphysema leading from lung tissue destruction. Increased activity of matrix metalloproteinases (MMPs) and an imbalance between MMPs and their tissue inhibitors (TIMPs) are considered as factors influencing the pathogenesis of COPD. We investigated the role of genetic polymorphism and expression level of MMP-9 and concentration of its complexes with TIMPs in the development of COPD among Polish patients. We analyzed SNP in the promoter region of

Indexed as

LungMatrix Metalloproteinase 9Polymorphism, Restriction Fragment LengthPulmonary Disease, Chronic ObstructiveAgedFemaleHumansMaleMiddle AgedPolandRespiratory Function TestsTissue Inhibitor of Metalloproteinase-1Tissue Inhibitor of Metalloproteinase-2Matrix Metalloproteinase 9MMP9 protein, humanTIMP1 protein, humanTIMP2 protein, humanTissue Inhibitor of Metalloproteinase-1Tissue Inhibitor of Metalloproteinase-2

Identifiers

PMID30643813
PMCPMC6311264
OpenAlexW2904680290

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.