Evidence map›Paper›PMID 30643799›Full record

ArticleBioMed research international2018

Homocysteine-Enhanced Proteolytic and Fibrinolytic Processes in Thin Intraluminal Thrombus and Adjacent Wall of Abdominal Aortic Aneurysm: Study In Vitro.

Aldona Siennicka, Marta Zuchowski, Kornel Chełstowski, Miłosław Cnotliwy, Jeremy Simon Clark, Maria Jastrzębska

Abstract read
In one paragraph

Article in BioMed research international, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Advanced Research of Abdominal Aortic Aneurysms on Metabolism.Frontiers in cardiovascular medicine · 2021
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Aldona SiennickaDepartment of Laboratory Diagnostics, Pomeranian Medical University, Szczecin, Poland.ORCID 0000-0002-5240-7676
Marta ZuchowskiDepartment of Laboratory Diagnostics, Pomeranian Medical University, Szczecin, Poland.
Kornel ChełstowskiDepartment of Laboratory Diagnostics, Pomeranian Medical University, Szczecin, Poland.
Miłosław CnotliwyDepartment of Vascular Surgery and Angiology, Pomeranian Medical University, Szczecin, Poland.
Jeremy Simon ClarkDepartment of Clinical and Molecular Biochemistry, Pomeranian Medical University, Szczecin, Poland.
Maria JastrzębskaDepartment of Laboratory Diagnostics, Pomeranian Medical University, Szczecin, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Homocysteine (Hcy) may affect the pathogenesis of abdominal aortic aneurysms (AAAs) through enhancement of proteolysis and an impaired coagulation/fibrinolysis system. Intensified haemostatic capacity may promote local proteolytic degradation of the aortic wall. This study aimed to examine the effects of Hcy on haemostatic and proteolytic processes in samples of thick and thin fragments of the ILT and underlying walls.

Indexed as

FibrinolysisProteolysisAgedAged, 80 and overAortic Aneurysm, AbdominalFemaleHomocysteineHumansMaleMatrix Metalloproteinase 2Middle AgedPlasminogenThromboplastinThrombosisTissue Plasminogen ActivatorHomocysteineMatrix Metalloproteinase 2MMP2 protein, humanPlasminogenThromboplastinTissue Plasminogen Activator

Identifiers

PMID30643799
PMCPMC6311307

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.