Evidence map›Paper›PMID 30643778›Full record

ArticleSkin appendage disorders2018

A Proposal for a New Severity Index for the Evaluation of Chronic Paronychia.

Güldehan Atış, Fatih Göktay, Zeynep Altan Ferhatoğlu, Emre Kaynak, Ayşegül Sevim Keçici, Şirin Yaşar, Sema Aytekin

Registry-linked trialOpen access · bronzeAbstract read
In one paragraph

Article in Skin appendage disorders, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06643416 (Efficacy and Safety of Add-on Topical Timolol in the Management of Epidermal Growth Factor and Anaplastic Lymphoma Kinase Receptor Tyrosine Kinase Inhibitor-induced Paronychia), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06643416 phase3recruitingnot on this mapstarted 2024, after this paper: background citation

Efficacy and Safety of Add-on Topical Timolol in the Management of Epidermal Growth Factor and Anaplastic Lymphoma Kinase Receptor Tyrosine Kinase Inhibitor-induced Paronychia: a Prospective Randomized Open-labelled Trial

TypeinterventionalSponsorQueen Mary Hospital, Hong KongRan2024 to 2025Enrolled40ConditionsParonychia, EGFR-TKI, ALK-TKIArmsTimolol 0.5% eye drops and betamethasone valerate 0.1% cream, Betamethasone valerate 0.1% cream
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Imbalanced Dermic Microbiome Aggravates Inflammation in Toenail Paronychia.Frontiers in cellular and infection microbiology · 2021
    Article
  2. Acute and Chronic Paronychia Revisited: A Narrative Review.Journal of cutaneous and aesthetic surgery
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Güldehan AtışDepartment of Dermatology, Haydarpaşa Numune Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.
Fatih GöktayDepartment of Dermatology, Haydarpaşa Numune Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.
Zeynep Altan FerhatoğluDepartment of Dermatology, Sultan Abdülhamid Han Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.
Emre KaynakDepartment of Dermatology, Tunceli State Hospital, Tunceli, Turkey.
Ayşegül Sevim KeçiciDepartment of Dermatology, Haydarpaşa Numune Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.
Şirin YaşarDepartment of Dermatology, Haydarpaşa Numune Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.
Sema AytekinDepartment of Dermatology, Haydarpaşa Numune Training and Research Hospital, University of Health Sciences, Istanbul, Turkey.
Sağlık Bilimleri Üniversitesi · TRHaydarpaşa Numune Eğitim ve Araştırma Hastanesi · TRMunzur University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionChronic paronychia (CP) is an inflammatory disease of the nail folds. Staging of CP is important for clinicians. We developed an objective scale that evaluates each finding of CP separately in addition to evaluating the treatment process and follow-up.

methodsA new "chronic paronychia severity index scale" was developed to enable dermatologists to examine all features of CP. A previous categorical severity scale and this new scale were used for the evaluation of CP by 6 different dermatologists. The dermatologists evaluated the nails with both scales again 20 days later using randomly ordered photographs.

resultsUsing the previous scale, the intra-observer intraclass correlation coefficient (ICC) values between the first and second evaluations were 0.767, 0.860, 0.734, 0.609, 0.900, and 0.840 for the 6 dermatologists. Using the new proposed scale, the intra-observer ICC values between the first and second evaluations were 0.930, 0.931, 0.942, 0.934, 0.938, and 0.920 for the 6 dermatologists. All intra-observer ICC values were higher for the results of the proposed scale than for those of the previous scale. The inter-observer ICC values were also higher for the proposed scale than for the previous scale for the 6 dermatologists.

conclusionThe new scale is a standardized, more suitable, objective, and valuable method to use in clinical practice and studies on CP.

Indexed as

NailParonychiaSeverity index

Identifiers

PMID30643778
PMCPMC6323378
OpenAlexW2806275152

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.