Evidence map›Paper›PMID 30643696›Full record

ArticlePeerJ2019

April DeLaurier, Cynthia Lizzet Alvarez, Kali J Wiggins

Open access · goldAbstract read
In one paragraph

Article in PeerJ, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Frontiers in physiology · 2022
    Article
  3. Article
  4. Article
  5. MutantPeerJ · 2020
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

April DeLaurierDepartment of Biology and Geology, University of South Carolina-Aiken, Aiken, SC, United States of America.
Cynthia Lizzet AlvarezDepartment of Biology and Geology, University of South Carolina-Aiken, Aiken, SC, United States of America.
Kali J WigginsDepartment of Biology and Geology, University of South Carolina-Aiken, Aiken, SC, United States of America.
University of South Carolina Aiken · US

Funding

South Carolina IDeA Networks of Biomedical Research (SC INBRE V)P20GM103499 · NIGMS · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI EDIE C GOLDSMITH · 2012 to 2026
$61.0M
NIGMS NIH HHS P20 GM103499
6 · The paper itself

Abstract

backgroundHistone deacetylases (HDACs) are epigenetic factors that function to repress gene transcription by removing acetyl groups from the N-terminal of histone lysines. Histone deacetylase 4 (HDAC4), a class IIa HDAC, has previously been shown to regulate the process of endochondral ossification in mice via repression of Myocyte enhancer factor 2c (MEF2C), a transcriptional activator of METHODS & MATERIALS: In this study, we generated two zebrafish lines with mutations in

resultsLines have insertions causing a frameshift in a proximal exon of DISCUSSION: Loss of function of

Indexed as

BoneCartilageCRISPR/Cas9hdac4PharyngealSkeletonZebrafish

Identifiers

PMID30643696
PMCPMC6329341
OpenAlexW2910180128

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.