Evidence map›Paper›PMID 30643439›Full record

ArticleInfection and drug resistance2019

Outpatient ertapenem therapy in an ESBL-high-prevalence area: an efficacy, safety, and cost study.

Arturo Ortiz-Álvarez, Mónica A Delgado-Ramírez, Montserrat Cuevas-Zúñiga, Teresa Hernández-Carrera, David Moncada Barrón, Daniel Aguilar Zapata, Rafael R Valdez Vázquez, Juan Pablo Ramírez-Hinojosa, Ana Patricia Rodríguez-Zulueta

Open access · goldAbstract read
In one paragraph

Article in Infection and drug resistance, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Review
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Arturo Ortiz-ÁlvarezDepartment of Infectious Disease, Hospital General Dr. Manuel GEA González, Mexico City, Mexico, rozu76@hotmail.com.
Mónica A Delgado-RamírezDepartment of Infectious Disease, Hospital General Dr. Manuel GEA González, Mexico City, Mexico, rozu76@hotmail.com.
Montserrat Cuevas-ZúñigaDepartment of Infectious Disease, Hospital General Dr. Manuel GEA González, Mexico City, Mexico, rozu76@hotmail.com.
Teresa Hernández-CarreraDepartment of Infectious Disease, Hospital General Dr. Manuel GEA González, Mexico City, Mexico, rozu76@hotmail.com.
David Moncada BarrónMicrobiology Laboratory, Hospital General Dr. Manuel GEA González, Mexico City, Mexico.
Daniel Aguilar ZapataDepartment of Infectious Disease, Hospital General Dr. Manuel GEA González, Mexico City, Mexico, rozu76@hotmail.com.
Rafael R Valdez VázquezDepartment of Infectious Disease, Hospital General Dr. Manuel GEA González, Mexico City, Mexico, rozu76@hotmail.com.
Juan Pablo Ramírez-HinojosaDepartment of Infectious Disease, Hospital General Dr. Manuel GEA González, Mexico City, Mexico, rozu76@hotmail.com.
Ana Patricia Rodríguez-ZuluetaDepartment of Infectious Disease, Hospital General Dr. Manuel GEA González, Mexico City, Mexico, rozu76@hotmail.com.
Hospital General Dr. Manuel Gea Gonzalez · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionOutpatient parenteral antimicrobial therapy is a safe, effective, and convenient way of administering antimicrobials for a wide variety of infections. So far there are no reports on the efficacy of outpatient antimicrobial therapy in Mexico. Our objective was to determine the outcomes, safety, and cost of outpatient ertapenem therapy (OET) in our hospital. PATIENTS AND

methodsA case series of 99 patients that received intravenous OET was conducted. The primary outcomes were clinical cure, relapse, and recurrence of infection.

resultsOf the 99 patients who received OET the most common diagnosis was urinary tract infection in 56%. Extended-spectrum-β-lactamase-producing Enterobacteriaceae caused 67% of infections in our population. Ninety-seven percent of the patients were cured at the completion of OET. One patient presented relapse 12 days after the end of OET; two patients presented recurrence, one with skin and soft tissue infection and one with pyelonephritis at days 35 and 34, respectively, after the end of OET. Three patients were readmitted after OET, one with an episode of phlebitis, one with recurrence, and one with relapse. A case of non-

conclusionIn our hospital, the OET was found to be effective, safe, and cost-saving when compared to inpatient care.

Indexed as

ertapenemESBLOPAT

Identifiers

PMID30643439
PMCPMC6312697
OpenAlexW2908053462

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.