Evidence map›Paper›PMID 30643415›Full record

ArticleTherapeutics and clinical risk management2019

Incidence rate and risk factors of early repolarization in patients with growth hormone-secreting pituitary adenoma: a cohort study.

Zhiyong Chen, Bin Hu, Yajuan Feng, Zongming Wang, Xiaobing Jiang, Yunjiu Cheng, Dongsheng He, Dimin Zhu, Zheng Xiao, Haijun Wang and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Therapeutics and clinical risk management, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Zhiyong ChenDepartment of Neurosurgery and Pituitary Tumor Center, The First Affiliated Hospital, SunYat-sen University, Guangzhou, People's Republic of China, wanghaij@mail.sysu.edu.cn; 25198960@qq.com.
Bin HuDepartment of Neurosurgery and Pituitary Tumor Center, The First Affiliated Hospital, SunYat-sen University, Guangzhou, People's Republic of China, wanghaij@mail.sysu.edu.cn; 25198960@qq.com.
Yajuan FengDepartment of Histology and Embryology, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, People's Republic of China.
Zongming WangDepartment of Neurosurgery and Pituitary Tumor Center, The First Affiliated Hospital, SunYat-sen University, Guangzhou, People's Republic of China, wanghaij@mail.sysu.edu.cn; 25198960@qq.com.
Xiaobing JiangDepartment of Neurosurgery, Sun Yat-sen University Cancer Center, Guangzhou, People's Republic of China.
Yunjiu ChengDepartment of Cardiology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, People's Republic of China.
Dongsheng HeDepartment of Neurosurgery and Pituitary Tumor Center, The First Affiliated Hospital, SunYat-sen University, Guangzhou, People's Republic of China, wanghaij@mail.sysu.edu.cn; 25198960@qq.com.
Dimin ZhuDepartment of Neurosurgery and Pituitary Tumor Center, The First Affiliated Hospital, SunYat-sen University, Guangzhou, People's Republic of China, wanghaij@mail.sysu.edu.cn; 25198960@qq.com.
Zheng XiaoDepartment of Neurosurgery and Pituitary Tumor Center, The First Affiliated Hospital, SunYat-sen University, Guangzhou, People's Republic of China, wanghaij@mail.sysu.edu.cn; 25198960@qq.com.
Haijun WangDepartment of Neurosurgery and Pituitary Tumor Center, The First Affiliated Hospital, SunYat-sen University, Guangzhou, People's Republic of China, wanghaij@mail.sysu.edu.cn; 25198960@qq.com.
Zhigang MaoDepartment of Neurosurgery and Pituitary Tumor Center, The First Affiliated Hospital, SunYat-sen University, Guangzhou, People's Republic of China, wanghaij@mail.sysu.edu.cn; 25198960@qq.com.
Sun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the incidence and risk factors for early repolarization (ER) in patients with growth hormone (GH)-secreting pituitary adenomas.

methodsFrom August 2014 to August 2016, patients with GH-secreting pituitary adenomas and non-functioning pituitary adenomas admitted to the First Affiliated Hospital, Sun Yat-sen University, were prospectively enrolled. Logistic regression analysis was used to investigate risk factors for ER development.

resultsA total of 118 patients with GH-secreting pituitary adenomas (41 with concomitant ER) and 103 patients with non-functioning pituitary adenomas were included. Compared with the non-functioning adenoma group GH and IGF-1 levels, left ventricular mass index (LVMI), and incidence of ER were significantly higher in the GH-secreting pituitary adenoma group (all

conclusionCompared with non-functioning pituitary adenoma patients, patients with GH-secreting pituitary adenomas have a significantly higher incidence of ER. Elevation of serum GH and IGF-1 had positive correlations with cardiac muscle cell hypertrophy and increased LVMI.

Indexed as

early repolarizationgrowth hormone-secreting pituitary adenomainsulin-like growth factorleft ventricle mass indexpituitary tumors

Identifiers

PMID30643415
PMCPMC6314049
OpenAlexW2907073966

What OpenQuestion holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.