Evidence map›Paper›PMID 30643299›Full record

ArticleNature neuroscience2019

Perceptual bias reveals slow-updating in autism and fast-forgetting in dyslexia.

Itay Lieder, Vincent Adam, Or Frenkel, Sagi Jaffe-Dax, Maneesh Sahani, Merav Ahissar

Open access · greenAbstract read
PubMed Publisher
In one paragraph

Article in Nature neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 98 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
98citing papers in PubMed, 3 pooled it
13.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

98 citing papers in PubMed, 3 syntheses or guidelines pooled it, 213 citations in OpenAlex.

  1. Pooled it
  2. Systematic Review and Meta-Analysis of Mismatch Negativity in Autism: Insights Into Predictive Mechanisms.Autism research : official journal of the International Society for Autism Research · 2025
    Pooled it
  3. Prediction in Autism Spectrum Disorder: A Systematic Review of Empirical Evidence.Autism research : official journal of the International Society for Autism Research · 2021
    Pooled it
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Rapid decay of perceptual memory in dyslexia.Trends in cognitive sciences · 2026
    Review
  10. Social communication development in a contingent world: insights from autism.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2026
    Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Intact Susceptibility to Visual Illusions in Autistic Individuals.Autism research : official journal of the International Society for Autism Research · 2025
    Article
  19. Article
  20. Article

38 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Itay LiederEdmond and Lily Safra Center for Brain Sciences, Hebrew University of Jerusalem, Jerusalem, Israel.ORCID http://orcid.org/0000-0003-4732-4267
Vincent AdamGatsby Computational Neuroscience Unit, London, UK.
Or FrenkelPsychology Department, Hebrew University, Jerusalem, Israel.
Sagi Jaffe-DaxPsychology Department, Princeton University, Princeton, NJ, USA.ORCID http://orcid.org/0000-0002-8759-6980
Maneesh SahaniGatsby Computational Neuroscience Unit, London, UK.ORCID http://orcid.org/0000-0001-5560-3341
Merav AhissarEdmond and Lily Safra Center for Brain Sciences, Hebrew University of Jerusalem, Jerusalem, Israel. msmerava@gmail.com.ORCID http://orcid.org/0000-0001-7694-8111
Hebrew University of Jerusalem · ILOxford Centre for Computational Neuroscience · GBPrinceton University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Individuals with autism and individuals with dyslexia both show reduced use of previous sensory information (stimuli statistics) in perceptual tasks, even though these are very different neurodevelopmental disorders. To better understand how past sensory information influences the perceptual experience in these disorders, we first investigated the trial-by-trial performance of neurotypical participants in a serial discrimination task. Neurotypical participants overweighted recent stimuli, revealing fast updating of internal sensory models, which is adaptive in changing environments. They also weighted the detailed stimuli distribution inferred by longer-term accumulation of stimuli statistics, which is adaptive in stable environments. Compared to neurotypical participants, individuals with dyslexia weighted earlier stimuli less heavily, whereas individuals with autism spectrum disorder weighted recent stimuli less heavily. Investigating the dynamics of perceptual inference reveals that individuals with dyslexia rely more on information about the immediate past, whereas perception in individuals with autism is dominated by longer-term statistics.

Indexed as

Acoustic StimulationAdultAuditory PerceptionAutism Spectrum DisorderAutistic DisorderDiscrimination, PsychologicalDyslexiaFemaleHumansMaleMemoryTime FactorsYoung Adult

Identifiers

PMID30643299
OpenAlexW2910569384

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.