ArticleNature neuroscience2019
Precise temporal memories are supported by the lateral entorhinal cortex in humans.
Article in Nature neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 75 papers.
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Who cites it
75 citing papers in PubMed, 170 citations in OpenAlex.
- Context-dependent abstraction of temporal relationships during naturalistic episodic memory.iScience · 2026Article
- Role of sparse episodic information in the progressive construction of event time about unknown narratives.Memory & cognition · 2026Article
- The Development of Temporal Memory for Complex Events.Developmental science · 2026Article
- Analysis of genetic mutation characteristics in 40 Chinese patients with hepatocellular carcinoma.Genes & genomics · 2026Article
- Interferences between time and space in advanced age.Memory & cognition · 2026Article
- Confidence in naturalistic decision making.Neuroscience of consciousness · 2026Article
- Spontaneous Oscillatory Activity in Episodic Timing: An EEG Replication Study and Its Limitations.eNeuro · 2026Article
- Neural Representation of Episodic Time.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Review
- The intrinsic time tracker: temporal context is embedded in entorhinal and hippocampal functional connectivity patterns.Nature communications · 2025Article
- Entorhinal cortex layer III Adgrl2 expression controls topographical circuit connectivity required for sequence learning.Translational psychiatry · 2025Article
- Models of human hippocampal specialization: a look at the electrophysiological evidence.Trends in cognitive sciences · 2025Review
- Shared spectral fingerprints of temporal memory precision and representation of the temporal structure of complex narratives.iScience · 2025Article
- Amyloid-Beta Deposition in Basal Frontotemporal Cortex Is Associated with Selective Disruption of Temporal Mnemonic Discrimination.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- Pattern integration and differentiation: Dual process model of episodic memory.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Multiplexing of temporal and spatial information in the lateral entorhinal cortex.Nature communications · 2024Article
- Time after Time: Preserving Temporal Memories When Experiences Repeat.Journal of cognitive neuroscience · 2024Review
- Amyloid-β deposition in basal frontotemporal cortex is associated with selective disruption of temporal mnemonic discrimination.bioRxiv : the preprint server for biology · 2024Article
- Selection of experience for memory by hippocampal sharp wave ripples.Science (New York, N.Y.) · 2024Article
- Multiplexing of temporal and spatial information in the lateral entorhinal cortex.bioRxiv : the preprint server for biology · 2024Article
- Distinct effects of slow and fast theta tACS in enhancing temporal memory.Imaging neuroscience (Cambridge, Mass.) · 2024Article
15 more citing papers are in PubMed but not listed here.
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3 authors at 2 institutions in 1 country.
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Abstract
There is accumulating evidence that the entorhinal-hippocampal network is important for temporal memory. However, relatively little is known about the precise neurobiological mechanisms underlying memory for time. In particular, whether the lateral entorhinal cortex (LEC) is involved in temporal processing remains an open question. During high-resolution functional magnetic resonance imaging (fMRI) scanning, participants watched a ~28-min episode of a television show. During the test, they viewed still-frames and indicated on a continuous timeline the precise time each still-frame was viewed during the study. This procedure allowed us to measure error in seconds for each trial. We analyzed fMRI data from retrieval and found that high temporal precision was associated with increased blood-oxygen-level-dependent fMRI activity in the anterolateral entorhinal (a homolog of the LEC in rodents) and perirhinal cortices, but not in the posteromedial entorhinal and parahippocampal cortices. This suggests a previously unknown role for the LEC in processing of high-precision, minute-scale temporal memories.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.