Evidence map›Paper›PMID 30643221›Full record

Observational studyEuropean journal of clinical nutrition2019

Healthy diets and telomere length and attrition during a 10-year follow-up.

Jelena Meinilä, Mia-Maria Perälä, Hannu Kautiainen, Satu Männistö, Noora Kanerva, Nitin Shivappa, James R Hébert, Patricia Iozzo, Maria Angela Guzzardi, Johan G Eriksson

Open access · greenAbstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in European journal of clinical nutrition, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 3 pooled it
5.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 3 syntheses or guidelines pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Influence of the Mediterranean Diet on Healthy Aging.International journal of molecular sciences · 2023
    Review
  13. Article
  14. Article
  15. Mediterranean diet and the hallmarks of ageing.European journal of clinical nutrition · 2021
    Review
  16. Article
  17. Nuts and Older Adults' Health: A Narrative Review.International journal of environmental research and public health · 2021
    Review
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 3 countries.

Jelena MeiniläFolkhälsan Research Center, Helsinki, Finland. Jelena.meinila@helsinki.fi.
Mia-Maria PeräläFolkhälsan Research Center, Helsinki, Finland.
Hannu KautiainenFolkhälsan Research Center, Helsinki, Finland.
Satu MännistöDepartment of Public Health Solutions, National Institute of Health and Welfare, Helsinki, Finland.
Noora KanervaDepartment of Public Health Solutions, National Institute of Health and Welfare, Helsinki, Finland.
Nitin ShivappaCancer Prevention and Control Program, University of South Carolina, Columbia, SC, 29208, USA.
James R HébertCancer Prevention and Control Program, University of South Carolina, Columbia, SC, 29208, USA.
Patricia IozzoInstitute of Clinical Physiology, National Research Council (IFC-CNR), Pisa, Italy.
Maria Angela GuzzardiInstitute of Clinical Physiology, National Research Council (IFC-CNR), Pisa, Italy.
Johan G ErikssonFolkhälsan Research Center, Helsinki, Finland.
Finnish Institute for Health and Welfare · FIFolkhälsans Forskningscentrum · FIIstituto di Fisiologia Clinica · ITUniversity of South Carolina · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTelomeres are repeats of DNA that contain the sequence TTAGGG at the ends of each chromosome, and their function is to protect DNA from damage. Little evidence exists regarding the relationship between dietary patterns and telomere length, especially derived applying longitudinal design. The aim was to study if overall dietary pattern is associated with leukocyte telomere length (LTL) or faster telomere attrition or both.

methodsThe setting was longitudinal and observational. Participants were 456 men and 590 women whose birth settled in between 1934 and 1944 and who participated in the Helsinki Birth Cohort Study. Baltic sea diet score (BSDS), modified Mediterranean diet score (mMED), and dietary inflammatory index (DII

resultsBSDS, mMED, and DII did not associate with LTL in the cross-sectional analysis in men or women. Higher mMED at baseline (2001-2004) was associated with slightly faster LTL shortening during the follow-up (standardized ß -0.08, 95% CI -0.15, -0.01). No association between mMED and LTL change was found in men. Adherence to BSDS and DII did not associate with LTL change in men or women.

conclusionBaltic sea diet, Mediterranean diet, and diet's inflammatory potential seem to have only little impact on telomere length and telomere attrition in elderly Finnish men and women.

Indexed as

Diet, HealthyCross-Sectional StudiesDietDiet, MediterraneanFemaleFinlandFollow-Up StudiesHumansInflammationLongitudinal StudiesMaleMiddle AgedSurveys and QuestionnairesTelomereTelomere Shortening

Identifiers

PMID30643221
OpenAlexW2910682978

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.