ArticleNature methods2019
A robust and versatile platform for image scanning microscopy enabling super-resolution FLIM.
Article in Nature methods, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.
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Who cites it
73 citing papers in PubMed.
- A computational super-resolution framework for multidimensional fluorescence imaging.Science advances · 2026Article
- 'In silico labelling': Exploring the biological landscape at the nanoscale using intelligent multimodal optical microscopy.Journal of microscopy · 2026Review
- A Dispersive Image Scanning Microscope for Multi-color High-resolution Imaging.ACS photonics · 2026Article
- Interferometric image scanning microscopy enables label-free super-resolution imaging of live cells.Light, science & applications · 2026Article
- Super-Resolution Structured Illumination Microscopy to Study Endocytosis and Cellular Nanoparticle Uptake.ACS nano · 2026Review
- Pinhole engineering based enhanced resolution (PEER) for fluorescence lifetime imaging microscopy.Communications biology · 2026Article
- Interferometric Image Scanning Microscopy for label-free imaging at 120 nm lateral resolution inside live cells.Light, science & applications · 2026Article
- Tracking DNA damage localization and chromatin remodeling in live cells using time-resolved quantitative analysis of DNA counterstains.Cellular and molecular life sciences : CMLS · 2026Article
- Computationally-designed aptamers targeting RAD51-BRCA2 interaction impair homologous recombination and induce synthetic lethality.Nature communications · 2025Article
- Fluorescence Lifetime Imaging Techniques-A Review on Principles, Applications and Clinical Relevance.Journal of biophotonics · 2025Review
- Single-Photon Single-Particle Tracking.bioRxiv : the preprint server for biology · 2025Article
- Image scanning microscopy based on multifocal metalens for sub-diffraction-limited imaging of brain organoids.Light, science & applications · 2025Article
- Pinhole Engineering based Enhanced Resolution (PEER) for Fluorescence Lifetime Imaging Microscopy.Research square · 2025Article
- High-fidelity tissue super-resolution imaging achieved with confocalLight, science & applications · 2025Article
- Wide-field fluorescence lifetime imaging of single molecules with a gated single-photon camera.Light, science & applications · 2025Article
- Open-source 3D active sample stabilization for fluorescence microscopy.Biophysical reports · 2025Article
- Deep compressed multichannel adaptive optics scanning light ophthalmoscope.Science advances · 2025Article
- Wavefront estimation through structured detection in laser scanning microscopy.Biomedical optics express · 2025Article
- HBimmCue: A Versatile Fluorescent Probe for Multi-Scale Imaging of Lipid Polarity and Membrane Order in Inner Mitochondrial Membrane.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- GSLab: open-source platform for advanced phasor analysis in fluorescence microscopy.Bioinformatics (Oxford, England) · 2025Article
13 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Image scanning microscopy (ISM) can improve the effective spatial resolution of confocal microscopy to its theoretical limit. However, current implementations are not robust or versatile, and are incompatible with fluorescence lifetime imaging (FLIM). We describe an implementation of ISM based on a single-photon detector array that enables super-resolution FLIM and improves multicolor, live-cell and in-depth imaging, thereby paving the way for a massive transition from confocal microscopy to ISM.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.