Evidence map›Paper›PMID 30643147›Full record

ArticleNature communications2019

Mature IgD

Avijit Ray, Mohamed I Khalil, Kirthi L Pulakanti, Robert T Burns, Cody J Gurski, Sreemanti Basu, Demin Wang, Sridhar Rao, Bonnie N Dittel

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Science translational medicine · 2025
    Article
  8. Article
  9. Article
  10. Severity of SARS-CoV-2 infection is linked to double-negative (CD27Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2022
    Article
  11. Article
  12. Review
  13. Discovery and Function of B-Cell IgD Low (BDJournal of molecular biology · 2021
    Review
  14. Review
  15. Review
  16. The primary tumor resection in patients with distant metastatic laryngeal carcinoma.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2020
    Article
  17. Harnessing Newton's third-law paradigm to treat autoimmune diseases and chronic inflammations.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Avijit RayBlood Research Institute, Versiti Wisconsin, Milwaukee, WI, USA.
Mohamed I KhalilBlood Research Institute, Versiti Wisconsin, Milwaukee, WI, USA.
Kirthi L PulakantiBlood Research Institute, Versiti Wisconsin, Milwaukee, WI, USA.
Robert T BurnsBlood Research Institute, Versiti Wisconsin, Milwaukee, WI, USA.
Cody J GurskiBlood Research Institute, Versiti Wisconsin, Milwaukee, WI, USA.
Sreemanti BasuBlood Research Institute, Versiti Wisconsin, Milwaukee, WI, USA.
Demin WangBlood Research Institute, Versiti Wisconsin, Milwaukee, WI, USA.
Sridhar RaoBlood Research Institute, Versiti Wisconsin, Milwaukee, WI, USA.ORCID http://orcid.org/0000-0003-2688-9541
Bonnie N DittelBlood Research Institute, Versiti Wisconsin, Milwaukee, WI, USA. bonnie.dittel@bcw.edu.ORCID http://orcid.org/0000-0003-4275-2457
Versiti Blood Center of Wisconsin · USMedical College of Wisconsin · USAbbVie (United States) · US

Funding

B cell responses in heparin-induced thrombocytopeniaR01HL130724 · NHLBI · VERSITI WISCONSIN, INC. · PI WANG, DEMIN · 2017 to 2024
$4.8M
PLC?s in B cell biology and autoimmunityR01AI079087 · NIAID · VERSITI WISCONSIN, INC. · PI WANG, DEMIN · 2008 to 2018
$4.4M
B cell-mediated immune regulationR56AI129348 · NIAID · VERSITI WISCONSIN, INC. · PI DITTEL, BONNIE N · 2017 to 2017
$451k
NHLBI NIH HHS R01 HL130724NIAID NIH HHS R01 AI079087NIAID NIH HHS R56 AI129348NIH HHS 1R56AI122655NIH HHS 1R56AI129348NIH HHS AI069358NIH HHS AI079087NIH HHS HL130724
6 · The paper itself

Abstract

A number of different B cell subsets have been shown to exhibit regulatory activity using a variety of mechanisms to attenuate inflammatory diseases. Here we show, using anti-CD20-mediated partial B cell depletion in mice, that a population of mature B cells distinguishable by IgD

Indexed as

Immune ToleranceAnimalsB-Lymphocyte SubsetsCells, CulturedCell SeparationCoculture TechniquesDermatitis, ContactDisease Models, AnimalFlow CytometryGene Expression ProfilingGene Expression Regulation, DevelopmentalHealthy VolunteersHumansImmunoglobulin DLeukocytes, MononuclearMiceImmunoglobulin DOxazoloneTnfsf18 protein, mouseTumor Necrosis Factors

Identifiers

PMID30643147
PMCPMC6331566
OpenAlexW2910477949

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.