Evidence map›Paper›PMID 30643135›Full record

ArticleNature communications2019

Suicide among cancer patients.

Nicholas G Zaorsky, Ying Zhang, Leonard Tuanquin, Shirley M Bluethmann, Henry S Park, Vernon M Chinchilli

Erratum issued Registry-linked trialAbstract read
In one paragraph

Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT07409584 (Mental Health and Suicidality in Glioblastoma Patients in Germany - a Multicenter Observational Study), which is not on this map. Cited by 164 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
164citing papers in PubMed, 8 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07409584 recruitingnot on this mapstarted 2026, after this paper: background citation

Mental Health and Suicidality in Glioblastoma Patients in Germany - a Multicenter Observational Study (SHINE-GLIO Study)

TypeobservationalSponsorUniversity Hospital, EssenRan2026 to 2028Enrolled180ConditionsGlioblastoma (GBM)ArmsMedical history, physical examination, completing questionnaires, data collection
3 · Its place in the literature

Who cites it

164 citing papers in PubMed, 8 syntheses or guidelines pooled it.

  1. Pooled it
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  6. Suicide Mortality Risk among Patients with Lung Cancer-A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2023
    Pooled it
  7. Guideline
  8. The Difficult Task of Diagnosing Depression in Elderly People with Cancer: A Systematic Review.Clinical practice and epidemiology in mental health : CP & EMH · 2021
    Pooled it
  9. Article
  10. Article
  11. Depression, non-medical pain prescriptions, and suicidal behavior in cancer survivors.Journal of cancer survivorship : research and practice · 2026
    Article
  12. Article
  13. Suicide among patients with cancer: a retrospective study of medical treatment-related factors associated with suicide.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
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104 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Nicholas G ZaorskyDepartment of Radiation Oncology, Penn State Cancer Institute, Hershey, PA, 17033, USA. nicholaszaorsky@gmail.com.ORCID http://orcid.org/0000-0002-4932-1986
Ying ZhangDepartment of Public Health Sciences, Penn State College of Medicine, Hershey, PA, 17033, USA.
Leonard TuanquinDepartment of Radiation Oncology, Penn State Cancer Institute, Hershey, PA, 17033, USA.
Shirley M BluethmannDepartment of Public Health Sciences, Penn State College of Medicine, Hershey, PA, 17033, USA.
Henry S ParkDepartment of Therapeutic Radiology, Yale School of Medicine, Smilow Cancer Hospital at Yale, 35 Park Street, New Haven, CT, 06511, USA.
Vernon M ChinchilliDepartment of Public Health Sciences, Penn State College of Medicine, Hershey, PA, 17033, USA.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
6 · The paper itself

Abstract

Our purpose is to identify cancer patients at highest risk of suicide compared to the general population and other cancer patients. This is a retrospective, population-based study using nationally representative data from the Surveillance, Epidemiology, and End Results program, 1973-2014. Among 8,651,569 cancer patients, 13,311 committed suicide; the rate of suicide was 28.58/ 100,000-person years, and the standardized mortality ratio (SMR) of suicide was 4.44 (95% CI, 4.33, 4.55). The predominant patients who committed suicide were male (83%) and white (92%). Cancers of the lung, head and neck, testes, bladder, and Hodgkin lymphoma had the highest SMRs ( > 5-10) through the follow up period. Elderly, white, unmarried males with localized disease are at highest risk vs other cancer patients. Among those diagnosed at < 50 years of age, the plurality of suicides is from hematologic and testicular tumors; if > 50, from prostate, lung, and colorectal cancer patients.

Indexed as

SurvivorshipAdultAgedAged, 80 and overAge FactorsFemaleHumansMaleMiddle AgedMortalityNeoplasmsRetrospective StudiesRisk AssessmentRisk FactorsSEER ProgramSex Factors

Identifiers

PMID30643135
PMCPMC6331593

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.