Evidence map›Paper›PMID 30643123›Full record

ArticleNature communications2019

Strigolactone perception and deactivation by a hydrolase receptor DWARF14.

Yoshiya Seto, Rei Yasui, Hiromu Kameoka, Muluneh Tamiru, Mengmeng Cao, Ryohei Terauchi, Akane Sakurada, Rena Hirano, Takaya Kisugi, Atsushi Hanada and 12 more

Abstract read
In one paragraph

Article in Nature communications, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 116 papers.

0numbers the graph read from it
0cells of the map it votes in
116citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

116 citing papers in PubMed.

  1. Negative feedback regulation of karrikin signaling inProceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Towards an integrated molecular understanding of plant hormones.Journal of integrative plant biology · 2026
    Review
  6. Article
  7. Mapping Strigolactone Hydrolysis in DWARF14 via QM/MM String Method.bioRxiv : the preprint server for biology · 2026
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. The Multifaceted Impact of Karrikin Signaling in Plants.International journal of molecular sciences · 2025
    Review
  18. Structural requirements of KAI2 ligands for activation of signal transduction.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  19. Article
  20. Article

56 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

22 authors.

Yoshiya SetoDepartment of Biomolecular Sciences, Graduate School of Life Sciences, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi, 980-8577, Japan. yoshiya@meiji.ac.jp.
Rei YasuiDepartment of Biomolecular Sciences, Graduate School of Life Sciences, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi, 980-8577, Japan.ORCID http://orcid.org/0000-0002-9386-1955
Hiromu KameokaGraduate School of Agricultural and Life Science, University of Tokyo, Yayoi, Bunkyo, Tokyo, 113-8657, Japan.ORCID http://orcid.org/0000-0002-7246-2242
Muluneh TamiruIwate Biotechnology Research Center, 22-174-4 Narita, Kitakami, Iwate, 024-0003, Japan.
Mengmeng CaoDepartment of Biomolecular Sciences, Graduate School of Life Sciences, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi, 980-8577, Japan.
Ryohei TerauchiIwate Biotechnology Research Center, 22-174-4 Narita, Kitakami, Iwate, 024-0003, Japan.
Akane SakuradaDepartment of Biomolecular Sciences, Graduate School of Life Sciences, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi, 980-8577, Japan.
Rena HiranoDepartment of Biomolecular Sciences, Graduate School of Life Sciences, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi, 980-8577, Japan.
Takaya KisugiDepartment of Biomolecular Sciences, Graduate School of Life Sciences, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi, 980-8577, Japan.
Atsushi HanadaDepartment of Biomolecular Sciences, Graduate School of Life Sciences, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi, 980-8577, Japan.
Mikihisa UmeharaRIKEN Plant Science Center, Tsurumi, Yokohama, Kanagawa, 230-0045, Japan.
Eunjoo SeoRIKEN Plant Science Center, Tsurumi, Yokohama, Kanagawa, 230-0045, Japan.
Kohki AkiyamaGraduates School of Life and Environmental Sciences, Osaka Prefecture University, 1-1 Gakuen-cho, Naka-ku, Sakai, Osaka, 599-8531, Japan.
Jason BurkeJack H. Skirball Center for Chemical Biology and Proteomics, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA.
Noriko Takeda-KamiyaRIKEN Plant Science Center, Tsurumi, Yokohama, Kanagawa, 230-0045, Japan.
Weiqiang LiRIKEN Plant Science Center, Tsurumi, Yokohama, Kanagawa, 230-0045, Japan.
Yoshinori HiranoStructural Biology Laboratory, Nara Institute of Science and Technology, 8916-5 Takeyama, Ikoma, Nara, 630-0192, Japan.
Toshio HakoshimaStructural Biology Laboratory, Nara Institute of Science and Technology, 8916-5 Takeyama, Ikoma, Nara, 630-0192, Japan.
Kiyoshi MashiguchiDepartment of Biomolecular Sciences, Graduate School of Life Sciences, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi, 980-8577, Japan.ORCID http://orcid.org/0000-0002-7234-887X
Joseph P NoelJack H. Skirball Center for Chemical Biology and Proteomics, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA.ORCID http://orcid.org/0000-0002-1277-0331
Junko KyozukaDepartment of Biomolecular Sciences, Graduate School of Life Sciences, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi, 980-8577, Japan.
Shinjiro YamaguchiDepartment of Biomolecular Sciences, Graduate School of Life Sciences, Tohoku University, 2-1-1 Katahira, Aoba-ku, Sendai, Miyagi, 980-8577, Japan. shinjiro@scl.kyoto-u.ac.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The perception mechanism for the strigolactone (SL) class of plant hormones has been a subject of debate because their receptor, DWARF14 (D14), is an α/β-hydrolase that can cleave SLs. Here we show via time-course analyses of SL binding and hydrolysis by Arabidopsis thaliana D14, that the level of uncleaved SL strongly correlates with the induction of the active signaling state. In addition, we show that an AtD14

Indexed as

Signal TransductionArabidopsisArabidopsis ProteinsCatalytic DomainHydrolysisLactonesMutationOryzaPlant Growth RegulatorsPlants, Genetically ModifiedReceptors, Cell SurfaceArabidopsis ProteinsDWARF14 protein, ArabidopsisLactonesPlant Growth RegulatorsReceptors, Cell Surface

Identifiers

PMID30643123
PMCPMC6331613

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.