Evidence map›Paper›PMID 30643011›Full record

SynthesisBioscience reports2019

Tumor necrosis factor gene polymorphisms are associated with silicosis: a systemic review and meta-analysis.

Min Zhang, Ling-Long Peng, Xue-Lei Ji, Hai-Bing Yang, Ri-Sheng Zha, Guo-Ping Gui

Open access · goldAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Bioscience reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Mechanisms of Environment-Induced Autoimmunity.Annual review of pharmacology and toxicology · 2021
    Article
  10. Tobacco Smoke Exposure Exacerbated Crystalline Silica-Induced Lung Toxicity in Rats.Toxicological sciences : an official journal of the Society of Toxicology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Min ZhangCentral Office, Suzhou National New and Hi-tech Industrial Development Zone Center for Disease Control and Prevention, Suzhou, Jiangsu 215011, China.
Ling-Long PengDepartment of Science and Education, The Second People's Hospital of Wuhu, Wuhu, Anhui 241000, China.
Xue-Lei JiDepartment of Science and Education, The Second People's Hospital of Wuhu, Wuhu, Anhui 241000, China.
Hai-Bing YangDepartment of Environmental Health, Suzhou Municipal Center for Disease Control and Prevention, Suzhou, Jiangsu 215004, China.
Ri-Sheng ZhaCentral Office, Suzhou National New and Hi-tech Industrial Development Zone Center for Disease Control and Prevention, Suzhou, Jiangsu 215011, China.
Guo-Ping GuiCentral Office, Suzhou National New and Hi-tech Industrial Development Zone Center for Disease Control and Prevention, Suzhou, Jiangsu 215011, China ggpszcn@126.com.
Wuhu Fourth People Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Studies investigating association between tumor necrosis factor (TNF) gene polymorphisms and silicosis susceptibility report conflicting results. The aim of this meta-analysis was to assess association between TNF gene polymorphisms and silicosis susceptibility. A systematic literature search was conducted to find relevant studies. Pooled odds ratios (ORs) with 95% confidence intervals (CIs) were used to estimate the strength of association. Finally, a total of 12 articles, involving 1990 silicosis patients and 1898 healthy controls were included in the meta-analysis. Overall, meta-analysis revealed a significant association between the TNF -308A allele and silicosis (OR = 1.348, 95%CI = 1.156-1.570,

Indexed as

Polymorphism, GeneticAsian PeopleGenetic Predisposition to DiseaseHumansOdds RatioSilicosisTumor Necrosis Factor-alphaTNF protein, humanTumor Necrosis Factor-alphameta-analysissilicosissusceptibilityTNF

Identifiers

PMID30643011
PMCPMC6361771
OpenAlexW2908730377

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.