Evidence map›Paper›PMID 30642954›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2019

Promises and perils of gene drives: Navigating the communication of complex, post-normal science.

Dominique Brossard, Pam Belluck, Fred Gould, Christopher D Wirz

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed.

  1. Article
  2. Questions and Consequences of Omics in Genetically Engineered Crop Regulation.Plant-environment interactions (Hoboken, N.J.) · 2025
    Review
  3. Article
  4. Article
  5. Genes drive organisms and slippery slopes.Pathogens and global health · 2024
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Conservation pest control with new technologies: public perceptions.Journal of the Royal Society of New Zealand · 2022
    Article
  16. Article
  17. Article
  18. An Outlook on Global Regulatory Landscape for Genome-Edited Crops.International journal of molecular sciences · 2021
    Review
  19. What we know about effective public engagement on CRISPR and beyond.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  20. Mobilizing molluscan models and genomes in biology.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dominique BrossardDepartment of Life Sciences Communication, University of Wisconsin-Madison, Madison, WI 53706; dbrossard@wisc.edu.ORCID 0000-0002-9188-8388
Pam BelluckThe New York Times, New York, NY 10018.
Fred GouldDepartment of Entomology and Plant Pathology, North Carolina State University, Raleigh, NC 27695.
Christopher D WirzDepartment of Life Sciences Communication, University of Wisconsin-Madison, Madison, WI 53706.

Funding

Combining Aedes aegypti genomics and modeling to improve gene drive strategies and our understanding of resistance evolutionR01AI139085 · NIAID · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI GOULD, FRED · 2018 to 2022
$1.9M
NIAID NIH HHS R01 AI139085
6 · The paper itself

Abstract

In November of 2017, an interdisciplinary panel discussed the complexities of gene drive applications as part of the third Sackler Colloquium on "The Science of Science Communication." The panel brought together a social scientist, life scientist, and journalist to discuss the issue from each of their unique perspectives. This paper builds on the ideas and conversations from the session to provide a more nuanced discussion about the context surrounding responsible communication and decision-making for cases of post-normal science. Deciding to use gene drives to control and suppress pests will involve more than a technical assessment of the risks involved, and responsible decision-making regarding their use will require concerted efforts from multiple actors. We provide a review of gene drives and their potential applications, as well as the role of journalists in communicating the extent of uncertainties around specific projects. We also discuss the roles of public opinion and online environments in public engagement with scientific processes. We conclude with specific recommendations about how to address current challenges and foster more effective communication and decision-making for complex, post-normal issues, such as gene drives.

Indexed as

CommunicationGene Drive TechnologyScienceDecision MakingHumansPublic Opiniongene drivespublic engagementscience communication

Identifiers

PMID30642954
PMCPMC6475393

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.