Evidence map›Paper›PMID 30642928›Full record

ArticleAntimicrobial agents and chemotherapy2019

Moxifloxacin in Chronic Obstructive Pulmonary Disease: Pharmacokinetics and Penetration into Bronchial Secretions in Ward and Intensive Care Unit Patients.

Maria Sionidou, Katerina Manika, Georgia Pitsiou, Paschalina Kontou, Kalliopi Chatzika, Paul Zarogoulidis, Ioannis Kioumis

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Maria SionidouPulmonary Department, Aristotle University of Thessaloniki, G. H. "G. Papanikolaou" (Exohi), Thessaloniki, Greece msionigeo@gmail.com ktmn05@yahoo.gr.
Katerina ManikaPulmonary Department, Aristotle University of Thessaloniki, G. H. "G. Papanikolaou" (Exohi), Thessaloniki, Greece msionigeo@gmail.com ktmn05@yahoo.gr.
Georgia PitsiouRespiratory Intensive Care Unit, Aristotle University of Thessaloniki, G. H. "G. Papanikolaou" (Exohi), Thessaloniki, Greece.
Paschalina Kontou1st Intensive Care Unit, G. H. "G. Papanikolaou" (Exohi), Thessaloniki, Greece.
Kalliopi ChatzikaPulmonary Department, Aristotle University of Thessaloniki, G. H. "G. Papanikolaou" (Exohi), Thessaloniki, Greece.
Paul ZarogoulidisPulmonary Department, Aristotle University of Thessaloniki, G. H. "G. Papanikolaou" (Exohi), Thessaloniki, Greece.
Ioannis KioumisPulmonary Department, Aristotle University of Thessaloniki, G. H. "G. Papanikolaou" (Exohi), Thessaloniki, Greece.
G. Papanikolaou General Hospital · GRAristotle University of Thessaloniki · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to evaluate the pharmacokinetic profile of moxifloxacin (MXF) in serum and sputum/bronchial secretions of 22 patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) hospitalized in the ward and intensive care unit (ICU). The data showed that ICU patients had lower concentrations in secretions (

Indexed as

AgedAnti-Bacterial AgentsBacterial InfectionsCritical CareDisease ProgressionFemaleHumansIntensive Care UnitsMaleMicrobial Sensitivity TestsMoxifloxacinProspective StudiesPulmonary Disease, Chronic ObstructiveAnti-Bacterial AgentsMoxifloxacinbronchial secretionsCOPDICUmoxifloxacinpharmacokinetics

Identifiers

PMID30642928
PMCPMC6395903
OpenAlexW2908586651

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.